溃疡性结肠炎发病机制的研究进展  

The research progress of the pathogenesis of ulcerative colitis

作　　者：陈璐[1] 周中银[1] 

机构地区：[1]武汉大学人民医院消化内科/消化系统疾病湖北省重点实验室,430060

出　　处：《疑难病杂志》2016年第6期650-654,共5页Chinese Journal of Difficult and Complicated Cases

基　　金：湖北省公益性科技计划项目(2013BkB013)

摘　　要：溃疡性结肠炎的发病机制较复杂,与多种因素联合作用有关。随着研究的进一步深入,目前认为集体免疫系统紊乱(如细胞因子、瘦素及脂联素等)起重要作用,此外还有遗传因素、环境因素和微生物感染等因素共同造成。了解溃疡性结肠炎的发病机制可为以后早期诊断、个体化治疗及预后评价提供线索,文章对其发病机制进行综述。The pathogenesis of ulcerative colitis is complicated,related to the joint action of multiple factors.With further research,now that the collective immune system disorders play an important rule,such as cytokines,leptin and adiponectin etc.There are also genetic factors,environmental factors and microbial infection factors and other factors caused together,Understanding the pathogenesis of ulcerative colitis can provide clues for future early diagnosis,individualized treatment and prognosis,the article reviewed its pathogenesis.

关 键 词：溃疡性结肠炎 发病机制 研究进展 

分 类 号：R574.62[医药卫生—消化系统]