^(18)F-FDG PET/CT显像对胃部恶性肿瘤的鉴别诊断价值  

The differential diagnostic value of ^(18)F-DG PET/CT imaging on gastric malignancies

作　　者：胡斌[1] 毛秋粉[1] 王锦锋[1] 谢新立[2] 

机构地区：[1]河南科技大学第一附属医院核医学科,河南洛阳471003 [2]郑州大学第一附属医院核医学科,郑州450052

出　　处：《重庆医学》2016年第16期2229-2232,共4页Chongqing medicine

摘　　要：目的探讨18F-FDG PET/CT显像对胃癌及原发性胃淋巴瘤(PGL)的鉴别诊断价值。方法选取2012年6月至2015年6月收治的93例胃癌(23例黏液腺癌及70例非黏液腺癌)及58例PGL[31例弥漫性大B细胞淋巴瘤(DLBCL)及27例黏膜相关组织淋巴瘤(MALT)]患者为研究对象,比较他们的临床资料、胃壁病灶的最大标准摄取值(SUVmax)、病灶最大厚度、CT值、病灶形态、合并脾肿大及肾门下淋巴结转移状况。采用Pearson相关分析SUVmax与病灶最大厚度的关系。结果胃癌组的平均年龄、病灶累及贲门的比例明显高于PGL组(P<0.05)。胃癌组的SUVmax及脾肿大发生率均显著低于PGL组(P<0.05)。病灶形态方面,胃癌组以Ⅱ型及Ⅲ型多见,而PGL组以Ⅰ型及Ⅱ型多见,两组比较有显著差异(P<0.05)。进一步分析表明DLBCL的SUVmax明显高于其他类型(P<0.05),病灶最大厚度明显大于胃黏液腺癌及MALT(P<0.05)。Pearson相关分析结果表明不同病理类型患者的SUVmax与病灶最大厚度之间均无显著相关(P>0.05)。结论 18F-FDG PET/CT检查在胃恶性肿瘤的鉴别诊断方面有重要意义,不同肿瘤、不同病理亚型患者在SUVmax、病灶最大厚度、病灶形态等方面有所不同。Objective To investigate the differential diagnostic value of 18F-DG PET/CT imaging on gastric malignancies and primary gastric lymphoma（PGL）. Methods A total of 93 cases of gastric cancer （2a cases of mucinous adenocarcinoma and 70 cases of non mucinous adenoearcinoma）,58 cases of PGL and 31 cases of Diffuse Large b Cell Lymphoma（DLBCL） and 27 cases of Mucosa associated tissue lymphoma （MALT） treated in our hospital from Jun 2012 to Jun 2015 were involved in this study. Their clinical data,SUVmax, maximum lesions thickness, CT value, lesion shape, merge splenomegaly and lymph node metastasis were compared. The relation between SUVmax and maximum lesions thickness were analyzed with Pearson analysis. Results The aver- age age and the lesions involve cardiac orifice rate of the gastric cancer group were significantly higher than that of PGL group（P〈 0.05）. The oecurence rate of SUVmax and splenomegaly in the gastric cancer group were significantly lower than that of PGL group （P〈O. 05）. From the perspective of lesion shape, type Ⅱ and Ⅲ were mostly found in gastric cancer group, while type Ⅰ and Ⅱ were mostly seen in PGL group,the difference was significant（P〈0.05）. Further analysis showed that the SUVmax of DLBCL was significantly higher than other type（P〈0.05） ;the maximum lesions thickness of DLBCL was significantly higher than gastric mucous adenocarcinoma and MALT（P〈0.05）. Pearson analysis showed that there was no significant difference between SUVmax of different pathological type and the maximum lesions thickness（P〈0. 05）. Conclasion The diagnostic value of 18F-FDG PET/CT in gastric malignancies was high, and patients with different cancer and pathological type were different in SUVmax, maximum lesions thickness and lesion shape.

关 键 词：正电子发射型计算机断层显像 胃肿瘤 原发性胃淋巴瘤 

分 类 号：R735.2[医药卫生—肿瘤] R730.44[医药卫生—临床医学]