反流性食管炎和非糜烂性食管反流病患者食管动力和pH监测的临床价值  

Clinical value of esop Hageal motility and p H monitoring in patients with reflux esop Hagitis and non erosive esop Hageal reflux disease

作　　者：侯天恩 曾德辉[1] 汪福群[1] 

机构地区：[1]广东省梅州市人民医院消化内科,514031

出　　处：《齐齐哈尔医学院学报》2016年第9期1181-1182,共2页Journal of Qiqihar Medical University

摘　　要：目的探讨反流性食管炎(RE)和非糜烂性食管反流病(NERD)患者食管动力和p H监测的意义。方法选取2013年8月至2015年8月来我院治疗的108例患者,根据诊断结果分为反流性食管炎组和非糜烂性食管反流病组(n=54),比较两组患者的食管动力和p H监测的结果。结果两组患者食管下括约肌(LESP)、食管体部(L3、L8、L13和L18)压力比较差异均无统计学意义(P>0.05),仅只有食管上括约肌压力(UESP)存在差异,RE组、UESP明显小于NERD组,差异有统计学意义(P<0.01)。两组患者的反流周期数和最长酸反流时间比较差异均无统计学意义(P>0.05),RE组长反流周期数明显大于NERD组,差异具有统计学意义(P<0.01)。结论反流性食管炎患者出现食管动力异常,同时酸暴露时间长可能是导致食管炎症的原因,临床中可针对性治疗。Objective To investigate the significance of esop Hageal motility and p H monitoring in patients with reflux esop Hagitis（ RE） and non erosive gastroesop Hageal reflux disease（ NERD）. Methods 108 patients treated in our hospital from August 2013 to August 2015 were divided into two groups according to the results of the diagnosis（ reflux esop Hagitis group,n = 54; non erosive reflux disease group,n = 54）. The results of esop Hageal motility and p H monitoring of the two groups were compared. Results There was no significant difference about the esop Hageal sp Hincter pressure（ LESP） and esop Hageal body pressure（ L3,L13,L8 and L18） between the two groups（ P 0. 05）,lower esop Hageal sp Hincter pressure（ UESP） of RE group was significantly less than NERD group（ P 0. 01）. There was no significant difference between the two groups about the reflux cycle number and the longest acid reflux time（ P 0. 05）. The number of the long reflux cycle of RE group was significantly greater than the NERD group,there was statistically significant（ P 0. 01）. Conclusions Abnormal esop Hageal motility occurs in patients with reflux esop Hagitis,and the long time of acid exposure may be the cause of esop Hageal inflammation,targeted clinical treatment can be helpful.

关 键 词：反流性食管炎 非糜烂性食管反流病 食管动力 PH 

分 类 号：R571[医药卫生—消化系统]