中晚期原发性肝癌住院患者死亡危险因素分析  

An Analysis of Risk Factors of Fatal Inpatients with Advanced Primary Hepatic Carcinoma

作　　者：杨敏[1] 王延风[1] 徐海燕[1] 吴晓明[1] 杨渤彦[1] 于雷[1] 

机构地区：[1]国家癌症中心/中国医学科学院北京协和医学院肿瘤医院,北京100021

出　　处：《中国肿瘤》2016年第6期438-441,共4页China Cancer

摘　　要：[目的]探讨影响中晚期原发性肝癌住院患者死亡的危险因素。[方法]回顾性分析83例中晚期原发性肝癌住院死亡患者的资料,从性别、年龄、乙型肝炎病毒感染、门静脉癌栓、Child-Pugh分级等方面研究影响患者死亡的因素,采用Cox比例风险回归模型进行单因素和多因素分析。[结果]全组患者中位生存时间为12.0月。Cox回归模型分析结果显示:乙型肝炎病毒感染、肿瘤治疗方式、门静脉癌栓、ECOG评分及Child-Pugh分级与中晚期原发性肝癌的预后相关。[结论]乙型肝炎病毒感染、门静脉癌栓、Child-Pugh分级是中晚期原发性肝癌的独立预后因素。[Purpose] To explore the risk factors of fatal inpatients with advanced primary hepatic carcinoma. [Methods] The clinic data of 83 cases with advanced primary hepatic carcinoma who died in hospital was retrospectively analyzed,and investigate from the gender,age,history of chronic hepatitis B,portal vein tumor thrombus,Child-Pugh classification and othen influence factors for survival,according to Cox proportional hazard model. [Results] The median survival for all patients was 12 months. The results of Cox regression analysis indicated that the Hepatitis B virus infection,treatment,portal vein tumor thrombus,ECOG score and Child-Pugh grade were significant prognostic factors. [Conclusions] The Hepatitis B virus infection,portal vein tumor thrombus and Child-Pugh grade are independent factors influencing fatal inpatients with advanced primary hepatic carcinoma.

关 键 词：原发性肝癌 死亡 危险因素 

分 类 号：R735.7[医药卫生—肿瘤]