痛泻要方与马来酸曲美布汀治疗肠易激综合征  

Tongxieyao Formula combined with Trimebutine Maleate in the Treatment of Irritable Bowel Syndrome

作　　者：吴石新 

机构地区：[1]河南省煤炭总医院中医科,郑州450002

出　　处：《光明中医》2016年第12期1794-1795,共2页GUANGMING JOURNAL OF CHINESE MEDICINE

摘　　要：目的探讨痛泻要方联合马来酸曲美布汀治疗腹泻型肠易激综合征的方法及临床疗效。方法将92例腹泻型肠易激综合征患者随机分为观察组与对照组各46例,对照组口服马来酸曲美布汀,观察组采用痛泻要方联合马来酸曲美布汀治疗,比较两组临床疗效及复发情况。结果观察组总有效率87.0%,对照组总有效率69.6%,组间比较差异显著(P<0.05);治疗后6个月内观察组复发率7.5%,对照组复发率28.1%,组间比较差异显著(P<0.05)。结论痛泻要方联合马来酸曲美布汀治疗腹泻型肠易激综合征能有效提高临床治疗效果,减少复发,适于临床推广应用。Objective To explore the methods and clinical effect of Tongxieyao formula combined with trimebutine maleate in the treatment of irritable bowel syndrome. Methods 92 patients with irritable bowel syndrome were randomly divided into observation group and control group,and each group had 46 patients. Patients in the control group were treated with trimebutine maleate. Patients in the observation group used Tongxieyao formula combined with trimebutine maleate. The clinical effect and relapse of the patients in the two groups were compared.Results The total effective rate of the observation group was 87. 0%,the total effective rate of the control group was 69. 6%,and there was a significant difference between the two groups（ P〈0. 05）. Within 6 months after the treatment,the recurrence rate of the observation group was 7. 5%,the recurrence rate of the control group was 28. 1%,and there was a significant difference between the two groups（ P〈0. 05）.Conclusion The Tongxieyao formula combined with trimebutine maleate in the treatment of irritable bowel syndrome can enhance the clinical therapeutic effect,reduce the relapse,and it is suitable to popularize and apply in clinic.

关 键 词：肠易激综合征 腹泻型 痛泻要方 马来酸曲美布汀 

分 类 号：R574.4[医药卫生—消化系统]