超声介导药物或基因传递的机制及研究进展  

The mechanism and progress of ultrasound mediated drug or gene delivery

作　　者：江云[1] 龚兰[1] 

机构地区：[1]华中科技大学同济医学院附属荆州医院超声科,湖北省荆州市434020

出　　处：《临床超声医学杂志》2016年第5期333-335,共3页Journal of Clinical Ultrasound in Medicine

摘　　要：超声是一种无创的、可视的治疗诊断模式,可用来追踪药物载体,触发药物释放,提高局部药物沉淀,且有很高的空间精度。超声介导药物或基因传递可以增加治疗效果和降低副作用。为了更详细地认识超声联合微泡介导药物传递的过程,以及进一步开发超声的治疗作用,本文就超声作用下微泡介导药物传递的机制作一综述。Ultrasound is a non -invasive and visual theranostic modality that can be used to track drug carriers,trigger drug release,and improve local drug sediment with high spatial precision. Ultrasound mediated drug or gene delivery can increase the therapeutic effect and reduce adverse reactions. To realize more details about the process of ultrasound microbubble mediated drug delivery,as well as the further development of ultrasonic treatment,this paper reviews on the mechanism of ultrasound microbubble mediated drug delivery.

关 键 词：微泡 基因传递 空化作用 超声 

分 类 号：R445.1[医药卫生—影像医学与核医学]