急性髓系白血病伴IgA-κ型M蛋白血症1例并文献复习  

Coexistence of acute myeloid leukemia and essential monoclonal gammopathy:a case report and literature review

作　　者：李宝林 李明[2] 王丽娜[2] 吕莹[2] 牟晓丽[2] 李卓[2] 李子坚[2] 席亚明[2] 

机构地区：[1]甘肃省定西市人民医院,甘肃定西743000 [2]兰州大学第一医院血液科血液病研究所

出　　处：《临床血液学杂志》2016年第3期419-420,共2页Journal of Clinical Hematology

摘　　要：急性髓系白血病（acute myeloid leukemia,AML）为原始粒细胞异常克隆增殖所致,易出现感染、发热、出血和贫血等;M蛋白血症为单克隆免疫球蛋白血症,具有恶病倾向;二者合并报道罕见。我们收治1例AML合并IgA-κ型M蛋白血症患者,现报告如下,并复习相关文献。We describe a case with simultaneous occurrence of acute myeloid leukemia （AML） and essential monoclonal gammopathy （EMG） of IgA-kappa. AML is caused by clonal proliferation of myeloblast and characterized by infiltration,infection, bleeding and anemia. EMG is defined as the presence of a serum monodonal immunoglobulin or a serum and urine monoclonal immunoglobulin light chain in the absence of evidence for B-cell tumor over a period of observation. EMG may harbinger the future development of a B-cell neoplasm,notably myeloma.

关 键 词：白血病 髓系 急性 单克隆丙种球蛋白病 

分 类 号：R733.71[医药卫生—肿瘤]