原发性皮肤CD30^+间变性大细胞淋巴瘤一例  

Primary cutaneous CD30^+ anaplastic large cell lymphoma:a case report

作　　者：石丽君[1] 高宇[1] 曹爱华[1] 

机构地区：[1]江苏省泰州市姜堰区皮肤病防治所,225500

出　　处：《中国麻风皮肤病杂志》2016年第6期354-356,共3页China Journal of Leprosy and Skin Diseases

摘　　要：患者,男,50岁。背部、前胸多发结节伴轻压痛半年余。皮损组织病理检查示:表皮角化过度、棘层肥厚;真皮全层及皮下组织间变性弥漫肿瘤细胞浸润、瘤细胞体积大,可见核分裂相。免疫组化结果:85%CD30强阳性,Ki-67约40%(+),CD3(++),LCA(+)。诊断:原发性皮肤CD30^+间变性大细胞淋巴瘤,T细胞型。A 50-year-old male presented with multiple nodules on the back and chest with mild tendernessover half a year.Biopsy showed epidermal hyperkeratosis,stratum spinosum hypertrophy,anaplastic diffuselarge lymphocytes in dermal layer and subcutaneous tissue and mitotic figure presented.Immunohistochemistry showed 85% cells of CD30（＋＋）,40% of Ki-67（＋）,CD3（＋＋）,LCA（＋）.The diagnosis of primary cutaneous CD30＋ anaplastic large cell lymphoma,T cell type was made.

关 键 词：淋巴瘤 CD30+间变 

分 类 号：R739.5[医药卫生—肿瘤]