内镜下套扎治疗食管静脉曲张破裂出血的临床观察  

Clinical study of endoscopic variceal ligation in treatment of esophageal variceal bleeding

作　　者：马娅梅[1] 石胜利[1] 沈洁[1] 

机构地区：[1]南方医科大学附属小榄医院消化内科,广东中山528415

出　　处：《吉林医学》2016年第6期1314-1316,共3页Jilin Medical Journal

摘　　要：目的:探讨内镜下套扎治疗食管静脉曲张出血的临床效果和安全性。方法:将136例中重度食管静脉曲张出血患者分为套扎组85例和对照组51例,套扎组进行内镜下套扎治疗,对照组采用内科药物保守治疗,比较两组患者的治疗有效率、再出血率及死亡率。结果:套扎组85例均成功套扎。套扎组的有效率为97.6%(83/85),显著高于对照组的0%(0/51),差异有统计学意义(P<0.05);套扎组的再出血率为18.8%(16/85),显著低于对照组的35.3%(18/51),差异有统计学意义(P<0.05);两组死亡率比较差异无统计学意义(P>0.05)。结论:内镜下套扎治疗食管静脉曲张安全有效,可有效预防再出血,可以作为治疗肝硬化合并食道静脉曲张出血的首选方法。Objective To analyze the clinical efficacy and safety of endoscopic variceal ligation in treatment of esophageal variceal bleeding. Method 136 patients with medium to high esophageal variceal bleeding were divided into the ligation and control groups,85 patients in ligation group were given endoscopic variceal ligation,and 51 patients in control group were given medical conservative treatment. The effective rate,rehemorrhage rate and mortality were compared. Results 85 patients who were given endoscopic variceal ligation were successfully. The rates of effective of ligation group was significantly higher than that of control group,the difference was statistically significant（ P〈0. 05）. The rehemorrhage rate of ligation group was significantly lower then that of control group,the difference was statistically significant（ P〈0. 05）. There was no significant difference in mortality of ligation group and control group（ P〉0. 05）. Conclusion Endoscopic variceal ligation is an safe and effective operation to treat esophageal variceal bleeding,and can effectively prevent rebleeding. It is a firstly method for the patients with esophageal variceal bleeding.

关 键 词：套扎 肝硬化 食管静脉曲张 出血 

分 类 号：R575.2[医药卫生—消化系统]