极低出生体重儿住院期间体重增长状况及影响因素  

Weight gain and its influencing factors in very low birth weight infants during hospitalization

作　　者：朱艳娜[1] 林洁冰[1] 梅家平[2] 何宝婷 李彦琦[3] 金宇[1] 郭丽[1] 陈亚军[1] 

机构地区：[1]中山大学公共卫生学院妇幼卫生系,广东广州510080 [2]深圳市妇幼保健院新生儿科 [3]丹麦哥本哈根大学生命学院运动与营养系

出　　处：《中国公共卫生》2016年第6期848-851,共4页Chinese Journal of Public Health

基　　金：国家自然科学基金(No.81302424);中山大学医科横向课题(与丹麦哥本哈根大学横向合作课题NEOMUNE项目)(510007103049)

摘　　要：目的了解极低出生体重儿住院期间体重增长情况,探讨影响体重增长速度的相关因素。方法回顾性调查深圳市妇幼保健院2011年1月1日—2012年12月31日期间住院的147例极低出生体重儿的临床资料,采用单因素和logistic多因素分析体重增长速度的影响因素。结果 147例极低出生体重儿中,体重增长速度中位数为12.77 g/(kg·d),宫外生长迟缓率为62.6%,适宜体重和高体重增长组的住院天数(P_(50)分别为48 d、36 d)小于低体重增长组P_(50)=56 d),高体重增长组宫外生长迟缓率(34.80%)小于适宜(65.30%)和低体重增长组(75.90%)(均P<0.05);多分类logistic回归分析显示,出生体重、体重恢复时间和达到全肠内营养时间与体重增长速度有关。结论大多数极低出生体重儿在住院期间体重增长缓慢,影响其体重增长速度的因素有出生体重、体重恢复时间和达到全肠内营养时间。Objective To investigate the weight gain in very low birth weight （VLBW）infants during hospitaliza- tion and its influencing factors. Methods Clinical data were collected retrospectively for VLBW infants admitted be- tween January 1,2011 and December 31,2012 in Shenzhen Women and Children＇s Hospital. Weight gain and its influen- cing factors in VLBW infants during the hospitalization were analyzed by logistic regression and single factor analysis. Results A total of 147 VLBW infants were included in the study. The median of weight gain velocity （WGV） was 12. 77 g/kg.d,and the incidence of extrauterine growth retardation （EUGR）was 62. 6%. The infants in the moderate weight gain velocity（MWGV）group （Ps0：56 d）had shorter duration of hospital stay than those in the low weight gain velocity （LWGV）and high weight gain velocity （HWGV） groups （Ps0：48 d ,3 6d）. In addition, the incidence of EUGR in HWGV group（34.80% ） was lower than that in the MWGV and LWGV groups （ 65.30% and 75.90% ） （ both P 〈 0. 05 ）. The results of logistic regression analysis showed that birth weight, time to regain birth weight, and time to achieve full enteral nutrition were related to the weight growth velocity. Conclusion Most VLBW infants have low WGV during hospitalization. Birth weight, time to regain birth weight and time to achieve full enteral nutrition are influencing factors for WGV in VLBW infants during hospitalization.

关 键 词：极低出生体重儿 体重增长 影响因素 

分 类 号：R153[医药卫生—营养与食品卫生学]