超声引导经皮穿刺125I放射性粒子组织间植入治疗胰腺癌安全性分析  

Safety analysis of ultrasound guided percutaneous 125I radioactive seed interstitial implantation for treatment of pancreatic cancer

作　　者：盖保东[1] 李清春[1] 杨冬艳[2] 

机构地区：[1]吉林大学中日联谊医院胃肠结直肠肛门外科,长春130031 [2]吉林大学中日联谊医院电诊科,长春130031

出　　处：《中华内分泌外科杂志》2016年第3期180-181,188,共3页Chinese Journal of Endocrine Surgery

基　　金：吉林省科委基金（3D513T903430）

摘　　要：目的明确超声引导经皮穿刺125I放射性粒子组织间植入治疗胰腺癌的临床安全性。方法回顾分析超声引导经皮穿刺125I放射性粒子组织间植入治疗的92例胰腺癌手术的安全性。结果所有92例均按治疗计划完成手术；术中穿刺针出血25例，出血量2—20ml，均顺利止血；误穿胰管2例，经保守治疗未见胰瘘；无误穿胆管病例；穿刺路径经胃肠道55例，术后未见消化道穿孔表现；未出现严重的术中、术后并发症。结论超声引导经皮穿刺，125I放射性粒子组织间植入治疗胰腺癌安全，可靠。Objective To make clear the clinical safety of ultrasound guided percutaneous 125I radioac- tive seed interstitial implantation for treatment of pancreatic cancer. Methods 92 cases of pancreatic cancer treated with ultrasound guided percutaneous 125I radioactive seed interstitial implantation were retrospectively analyzed. Results All the 92 cases were performed successfully according to the preoperative plan. 25 cases suf- fered puncture-hemorrhage and blood loss about 2 to 20 ml, and all got hemostasis successfully. 2 cases had pan- creatic duct injury during puncture, but no pancreatic fistula was found after conservative treatment. No case had bile duct injury. No digestive tract perforation occurred in tile 55 cases whose puncture path was through the gastrointestinal tract. No serious complications occurred during the surgery. Conclusions Ultrasound guided percutaneous 125I radioactive seed interstitial implantation for treatment of pancreatic cancer is safe and reliable.

关 键 词：125碘 胰腺癌 近距离肿瘤放射治疗 安全 

分 类 号：R735.9[医药卫生—肿瘤]