游离DNA(cfDNA)在膀胱癌中的研究进展  

Research progress of cell-free DNA in bladder cancer

作　　者：刘安伟[1] 曾蜀雄[1] 陈新[1] 马重[1] 许传亮[1] 

机构地区：[1]第二军医大学附属长海医院泌尿外科,上海200433

出　　处：《临床泌尿外科杂志》2016年第6期570-574,共5页Journal of Clinical Urology

摘　　要：游离DNA(cell-free DNA,cfDNA),又称循环DNA,是存在于血液、尿液中游离于细胞外的DNA。作为一种新型的诊断标志物,其应用价值在多种实体肿瘤中得以证实。在膀胱癌的研究中,游离DNA具备独特的优势,尤其在早期诊断膀胱癌方面具有巨大的潜能。Cell-free DNA（cfDNA）,also called circulating DNA,is one kind of DNA which is independent of cell in blood and urine.As a novel diagnostic biomarker,the clinical value of cfDNA has been validated in various malignant solid tumors.In bladder cancer research,cfDNA possesses unique superiority and tremendous potential,especially in early diagnosis of bladder cancer.

关 键 词：游离DNA 循环DNA 膀胱癌 早期诊断 

分 类 号：R737.14[医药卫生—肿瘤]