自噬与甲状腺癌  

Autophagy and thyroid cancer

作　　者：曹乐薇 乔虹[1] 

机构地区：[1]哈尔滨医科大学附属第二医院内分泌五病房,哈尔滨150081

出　　处：《中国医师杂志》2016年第6期950-953,共4页Journal of Chinese Physician

基　　金：国家自然科学基金（81172742、81473053）;黑龙江省自然科学基金重点项目（ZD201220）

摘　　要：甲状腺癌的发病率很高；从整个内分泌系统恶性肿瘤的发病率来看，它的发病率居于首位；从全身恶性肿瘤的发病率来看，其发病率约为1％。甲状腺癌主要分为四类：甲状腺乳头状癌、髓样癌、未分化癌以及甲状腺滤泡状癌。近来，自噬对甲状腺癌发病的影响，以及自噬在甲状腺癌治疗中的作用已经成为研究的热点。现就自噬与甲状腺癌之间的关系作一简要阐明。The incidence rate of thyroid cancer is very high with the first place of the incidence in the whole endocrine system of malignant tumors, and about 1% from the incidence of systemic malignant tumors. Thyroid carcinoma is mainly divided into four types： papillary thyroid carcinoma, medullary thyroid carcinoma, undifferentiated thyroid carcinoma, and follicular thyroid carcinoma. Recently, the effect of autophagy on the incidence of thyroid cancer as well as the role of macrophages in the treatment of thyroid cancer has become a hot research. Here, a brief review will be carried out on the relationship between autophagy and thyroid cancer.

关 键 词：自噬 甲状腺肿瘤 综述 

分 类 号：R736.1[医药卫生—肿瘤]