干眼检查中泪膜破裂时间测定对泪河高度的影响  

Dry Eye Examination in the Tear Film Break-up Time of Tears River Height Determination

作　　者：徐清妍 钟瑞生 郑玛丽[1] 郭连春 

机构地区：[1]厦门市中医院眼科,福建厦门361009

出　　处：《中外医疗》2016年第17期51-53,共3页China & Foreign Medical Treatment

摘　　要：目的研究在进行泪河高度(TMH)测量时非侵入性泪膜破裂时间测定(NIK-BUT)对其的影响。方法整群选取2015年3月—2015年6月在厦门市中医院眼科就诊的63例干眼患者及63名常规体检的健康人,所有入选者都用Keratograph 5M眼表综合分析仪(OCULUS,德国)拍摄泪河的图片,记录基础泪河高度(△TMH),并在非侵入性泪膜破裂时间检查前后分别测量泪河高度。泪膜破裂时间检查要求受检者尽量保持不眨眼,并在下一次眨眼后停止检查。结果健康人群及干眼患者的基础TMH(△TMH)分别为(0.24±0.06)mm和(0.14±0.04)mm。干眼患者基础TMH值显著低于健康人群TMH(P<0.001)。在行NIK-BUT检查后TMH值显著增加,健康人群TMH增加(0.12±0.08)mm,干眼患者TMH增加(0.06±0.09)mm(P<0.001,P=0.026)。结论在用眼表综合分析仪检测干眼患者时,泪河高度测量应该在泪膜破裂时间检查等强制性眨眼动作前完成。Objective To study the effect of non-invasive break-up time（NIK-BUT） measurement on tear meniscus height（TMH） assessment. Methods Group selection 63 patients with dry eye and 63 normal subjects who treated in Xiamen Hospital of TCM from March 2015 to June 2015 were enrolled.Lower tear meniscus images were captured, the baseline TMH（△TMH） was measured,and then recorded TMH values before and after NIK-BUT measurements in each subject with Keratograph 5M（OCULUS,Germany）. NIK-BUT measurements need all subjects to keep their eyes open as long as possible until the next blink. Results The △TMH values of the normal and dry eye groups were（0.24±0.06）mm and（0.14±0.04）mm.The △TMH values of dry eye patients were significantly lower than normal subjects（P〈0.001）. Significant increases in TMH values were observed in both normal subjects（0.12±0.08）mm and dry eye patients（0.06±0.09）mm after NIK-BUT measurement（P〈0.001, P=0.026）. Conclusion On the diagnosis of dry eye with Keratograph 5M,TMH should be assessed before tests that require forced eye opening such as NIK-BUT.

关 键 词：干眼 泪河高度测量 非侵入性泪膜破裂时间 

分 类 号：R777[医药卫生—眼科]