细胞凋亡对衰老的调节在肿瘤的发生发展及治疗的研究进展  

The regulation of apoptosis on aging and the research progress of in tumor development and treatment

作　　者：唐珍[1] 易芳[1] 郭冬梅[1] 王含彦[1] 

机构地区：[1]川北医学院生物化学教研室,四川南充637000

出　　处：《暨南大学学报（自然科学与医学版）》2016年第3期215-220,共6页Journal of Jinan University(Natural Science & Medicine Edition)

基　　金：国家自然科学基金项目(81160141);川北医学院科研基金项目(CBY15-A-YB27)

摘　　要：细胞凋亡是细胞死亡的一种形式,是调节机体正常发育的重要机制,涉及一系列在维持细胞自稳中发挥重要作用的调控因子.肿瘤的发生、发展与治疗也受到凋亡调控蛋白的调控,细胞凋亡也参与多种与衰老相关的病理过程,本研究就细胞凋亡通路及其对衰老及肿瘤的相关调控机制进行综述.Apoptosis is a form of cell death, which is an important mechanism that regulates body＇ s normal development and involves a series of regulatory factors. It is important that these regulators play critical roles in maintenance of the body. Apoptosis regulatory proteins also affect tumor occurrence, development and treatment and a variety of age-related pathological processes. This review summarized apoptosis pathways and the mechanisms involved in the of regulation of aging and cancer.

关 键 词：细胞凋亡 凋亡通路 衰老 癌症 作用机理 

分 类 号：R362[医药卫生—病理学]