进展期胃癌胃周淋巴结的128层CT灌注成像研究  

Research on 128-slice CT perfusion imaging of perigastric lymph node metastases of advanced gastric cancer

作　　者：左晓娜[1] 曲红光[1] 王治民[1] 

机构地区：[1]甘肃省人民医院放射科,甘肃兰州730000

出　　处：《甘肃医药》2016年第7期487-490,共4页Gansu Medical Journal

摘　　要：目的:通过胃癌128层螺旋CT灌注成像研究,探讨胃周转移性淋巴结与活动期反应增生性淋巴结及静止期反应增生性淋巴结灌注曲线及灌注功能图像特征及胃癌胃周不同类型淋巴结灌注参数(血流量、血容量、平均通过时间、表面通透性)的差异。方法:选取甘肃省人民医院经手术病理证实的30例胃癌患者中的转移性淋巴结(A组)35枚,活动期反应增生性淋巴结(B组)53枚,静止期反应增生性淋巴结(C组)27枚,比较三组间的时间-密度曲线(time-density cuver,TDC)的差异,利用单因素方差分析比较不同组间各灌注参数的差异。结果:(1)128层螺旋CT灌注成像能提供胃癌胃周不同类型淋巴结内部的血流灌注信息,能准确地反映淋巴结的生理功能情况。(2)转移性淋巴结、活动期反应增生性淋巴结及静止期反应增生性淋巴结的BF.BV.MTT.PS值均存在差异。结论:128层螺旋CT胃癌灌注成像能直观地反映胃癌胃周淋巴结的灌注参数的改变,并较客观地、量化地反映了淋巴结组织内部血流动力学的改变,结合增强图像和多种后处理技术,可为胃癌胃周淋巴结的定位、定性诊断及胃癌术前分期评估提供更有价值的信息。因此CT灌注成像技术是一种新的无创性的用于评价组织、器官血流灌注状态的功能成像方法。Objective：By studying the 128-slice spiral CT perfusion imaging of gastric cancer,this study aimed to investigate the per-fusion curves and perfusion imaging features of metastatic perigastric lymph nodes,reactive lymphoid hyperplasia（RLH） in the active stageand RLH in the quiescent stage;to find out the differences of the perfusion indexes including blood flow（BF）,blood volume（BV）,mean transittime（MTT） and permeability surface（PS） of the different types of lymph nodes in advanced gastric cancer.Methods：From the 30 patients withgastric cancer diagnosed by surgery and pathological examination admitted in Gansu Provincial Hospital,35 metastatic lymph nodes（GroupA）,53 lymph nodes with reactive lymphoid hyperplasia（RLH） in the active stage（Group B） and 27 RLH lymph nodes in the quiescent stagewere selected,and the time-density curves（TDC） of the three groups were compared,then the differences of the perfusion indexes were com-pared and analyzed by one-way analysis of variance（one-way ANOVA）.Results：1The 128-slice spiral CT perfusion imaging of gastric can-cer could demonstrate the perfusion information inside the different types of perigastric lymph nodes,and could reflect the physiological func-tions of the lymph nodes precisely;2The results of BF,BV,MTT and PS of metastatic perigastric lymph nodes,RLH lymph nodes in the reac-tive stage and RLH lymph nodes in the quiescent stage were statistically different.Conclusion：The 128-slice spiral CT perfusion imaging ofgastric cancer can reflect the changes of the perfusion indexes of perigastric lymph nodes visually,and can provide the objective and quantita-tive information of thehemodynamic changes of the lymph nodes.Combined with enhanced imaging and various post-processing technologies,the 128-slice spiral CT perfusion imaging can provide more valuable information for thelocating and the qualitative diagnosis of the perigastriclymph nodes and the preoperative staging evaluation.Therefore,CT perfusion imaging is a new,non-

关 键 词：胃癌 灌注成像 体层摄影术 X线计算机 

分 类 号：R743.330.4[医药卫生—神经病学与精神病学]