老年女性冠心病并发抑郁症的临床研究  

Clinical study on the elderly female patients with coronary heart disease complicated with depression

作　　者：葛红敏[1] 尚嫄嫄[2] 崔开艳[3] 董苒[1] 

机构地区：[1]天津市安定医院,天津300222 [2]山东大学齐鲁医院 [3]山东省精神卫生中心

出　　处：《国际精神病学杂志》2016年第3期461-463,476,共4页Journal Of International Psychiatry

摘　　要：目的分析老年女性冠心病患者并发抑郁症的发病情况和临床特点。方法于2012年1月~2014年3月,抽取100例老年女性冠心病患者作为此次研究的对象,应用汉密尔顿抑郁量表（HAMD）进行评估,根据评估结果分为冠心病合并抑郁症组（观察组）和冠心病未合并抑郁症组（对照组）,并对比分析冠心病合并抑郁症的临床症状、发生原因,以及两组患者的动态心电图监测结果和死亡情况。结果老年女性冠心病合并抑郁症的发病率为54%,其临床症状主要为抑郁情绪、睡眠障碍、兴趣减退等。动态心电图监测结果显示,与对照组相比,观察组的室性心律失常、房性心律失常以及缺血性ST-T波段改变等发生率均明显更高（P〈0.05）。随访发现,与对照组相比,观察组的两年内死亡率明显更高（P〈0.05）。结论老年女性冠心病患者并发抑郁症的概率较高,且多表现出抑郁症的核心症状,其预后较差,临床上应对该疾病患者进行积极有效的治疗。Objective To analyze and explore the incidence and clinical features of elderly female patients with coronary heart disease complicated with depression. Methods From January 2012 to March 2014,100 elderly female patients with coronary heart disease were selected for this research,and the Hamilton Depression Rating Scale（HAMD）of the two groups were evaluated and compared.According to the evaluation results,100 patients were divided into coronary heart disease with depression group（observation group）and coronary heart disease without depression group（control group）,then analyzing the clinical symptoms and causes of coronary heart disease combined with depression,and to compare the results of dynamic ECG monitoring and the death of the two groups. Results The incidence of coronary heart disease in elderly women with depression was 54%,the main clinical symptoms were depression mood,sleep disorders,loss of interests,and so on. Dynamic ECG monitoring results showed,compared with control group,the incidences of ventricular arrhythmias,atrial arrhythmias and ischemic ST-T band changes of observation group were significantly higher（P〈0.05）. Follow-up found,compared with control group,the mortality rate was significantly higher in the observation group（P〈0.05）. Conclusion The elderly female patients with coronary heart disease patients have a high probability of depression,and more show the core symptoms of depression,the prognosis is also poor. Thus,the clinical response to these patients should be more active and effective.

关 键 词：老年女性 冠心病 抑郁症 临床特点 

分 类 号：R749.4[医药卫生—神经病学与精神病学]