原子吸收法测定注射用三磷酸腺苷二钠氯化镁中氯化镁含量  

Determination of Magnesium Chloride in Adenosine Disodium Triphosphate and Magnesium Chloride for Injection by AAS

作　　者：冉晓静 冉大强[2] 王波 

机构地区：[1]山东省食品药品检验研究院,济南250101 [2]山东省药品审评认证中心,济南250014

出　　处：《中国药品标准》2016年第3期179-181,共3页Drug Standards of China

摘　　要：目的：建立注射用三磷酸腺苷二钠氯化镁中氯化镁含量测定的原子吸收法。方法：采用火焰原子吸收标准曲线法，检测波长为285.2 nm。结果：镁离子在浓度0.12～0.28μg＆#183; mL－1的范围内，线性关系良好（ r＝0.9998），精密度、回收率良好。结论：该方法可以准确测定注射用三磷酸腺苷二钠氯化镁中氯化镁含量，不受其他成分的影响，可用于注射用三磷酸腺苷二钠氯化镁的质量控制。Objective：To establish an AAS method for determining the content of Magnesium Chloride in Adenosine Disodium Triphos -phate and Magnesium Chloride for Injection.Method：A calibration curve method of flame atomic absorption spectrometry was adopt-ed.The detection wavelength was set at 285.2 nm.Results：The concentration of Magnesium had a good linearity in the range of 0.12-0.28 μg＆#183; mL-1（r=0.999 8）, the precision and recovery rate was good.Conclusion：The method is accurate and do not be inter-fered by other ingredients.It can be used for the quality control of Adenosine Disodium Triphosphate and Magnesium Chloride for Injec -tion.

关 键 词：原子吸收法 注射用三磷酸腺苷二钠氯化镁 氯化镁 含量测定 

分 类 号：R921.2[医药卫生—药学]