牙齿脱敏剂对釉质再矿化的体外研究  

Study on the remineralization effect of Aominqing Dental desensitizer on initial enamel lesions in vitro

作　　者：刘子晗[1] 郑红[1] 徐疾[1] 李静[1] 周淑[1] 

机构地区：[1]南京医科大学附属南京儿童医院,210008

出　　处：《实用医学杂志》2016年第12期1930-1933,共4页The Journal of Practical Medicine

基　　金：江苏省预防医学科研基金资助项目(编号:Y2013003)

摘　　要：目的:通过体外实验的方法对奥敏清牙齿脱敏剂、含氟牙膏对脱矿釉质再矿化的作用进行比较。方法:63颗离体牙人工脱矿后随机分为3组,分别使用奥敏清牙齿脱敏剂、1.1 g/L含氟牙膏、去离子水进行再矿化处理8 d,激光扫描共聚焦显微镜(CLSM)观察釉质切片并定量分析、扫描电镜(SEM)观察釉质表面形态。结果:CLSM数据显示奥敏清处理组及含氟牙膏处理组荧光面积(A)分别为(3.19±0.19)×10~4、(3.61±0.26)×10~4μm^2,总荧光量(TF)分别为(0.61±0.09)×106、(0.89±0.15)×106,平均荧光量(AF)分别为(18.98±1.56)、(24.65±2.39),均低于空白对照组[A=(4.89±0.24)×10~4μm2,TF=(1.78±0.21)×10~6,AF=36.29±2.57](P<0.01);奥敏清处理组的各参数值低于含氟牙膏处理组(P<0.05)。SEM观察奥敏清处理组釉质表面形态最平整,含氟牙膏处理组次之,空白对照组最为粗糙。结论:本实验条件下,奥敏清牙齿脱敏剂及1.1 g/L含氟牙膏对脱矿釉质均有再矿化作用,奥敏清牙齿脱敏剂的作用更强。Objective To investigate the remineralization effects of the Aominqing dental desensitizer and the fluoride dentifrice on the demineralized enamels. Methods Sixty-three teeth were randomly divided into three groups after demineralization , then was remineralized for eight days by using Aominqing dental desensitizer, fluoride dentifrice （1.1 g/L）, and deionized water, respectively. The thin sections of teeth were analyzed under the con-focal laser scanning microscope （CLSM）. The morphology of the surface of teeth was observed under the scanning electron microscope （SEM）. Results Under CLSM, the evaluation parameter area of the fluorescent lesion （A,μm2） processed by Aominqing and by fluoride was （3.19 ± 0.19） × 104, （3.61 ± 0.26） × 104 μm2, respectively. The total fluorescence （TF） was （0.61 ± 0.09） × 106, （0.89 ± 0.15） × 106, average fluorescent of the lesion（AF） was （18.98 ± 1.56）, （24.65 ± 2.39）, and the above parameters were all less than those in the blank control group [A=（4.89 ± 0.24） × 104 μm2,TF=（1.78 ± 0.21） × 106, AF = 36.29 ± 2.57] （P 〈 0.01）. The evaluation parameters in the Aominqing group were less than those in the fluoride dentifrice group（P 〈 0.05）. Under SEM, the surface of the group processed by Aominqing was the smoothest, compared to the fluoride dentifrice group and the blank control group. Conclusions Both Aominqing dental desensitizer and fluoride dentifrice （1.1 g/L） have the remineralization effects on the demineralized enamels, and the former has a stronger effect.

关 键 词：釉质 再矿化 氟化物 

分 类 号：R781.1[医药卫生—口腔医学]