轻中度青少年特发性脊柱侧凸患者肺功能研究  

A study on pulmonary function in patients with mild-to-moderate adolescent idiopathic scoliosis

作　　者：杜青[1] 周璇[1] 陈楠[1] 杨晓颜[1] 梁菊萍[1] 孙锟[2] 

机构地区：[1]上海交通大学医学院附属新华医院康复医学科,上海200092 [2]上海交通大学医学院附属新华医院儿心血管科

出　　处：《中国康复医学杂志》2016年第7期752-755,共4页Chinese Journal of Rehabilitation Medicine

基　　金：上海市科学技术委员会资助项目(13401903400);崇明县科学技术委员会资助项目(CKY2013-03);上海市残联系统康复人才培养三年行动计划优秀学科带头人项目

摘　　要：目的:研究轻中度青少年特发性脊柱侧凸(adolescent idiopathic scoliosis,AIS)患者肺功能特征。方法:选取68例AIS患者作为AIS组,20例健康青少年作为正常对照组,采用肺功能仪测定研究对象用力肺活量(FVC)、FVC预计值(FVC pred)、FVC占预计值百分数(FVC pred%)、第1秒用力呼气量(FEV1)、FEV1预计值(FEV1 pred)、FEV1占预计值百分数(FEV1 pred%)、FEV1占FVC百分数(FEV1/FVC%)。结果:AIS组FEV1 pred%、FEV1/FVC%分别为(85.60±11.60)、(88.40±6.84),对照组分别为(93.20±9.39)、(91.00±3.13),AIS组FEV1 pred%、FEV1/FVC%均低于正常对照组,差异有显著性意义。不同侧凸类型、不同性别AIS患者FVC pred%、FEV1 pred%、FEV1/FVC%差异无显著性意义。患者年龄与FVC、FVC pred、FEV1、FEV1 pred正相关,患者Cobb角与肺功能指标无关。结论:轻、中度AIS患者存在肺功能障碍,患者肺功能与年龄正相关,与侧凸类型、性别、Cobb角没有相关性。Objective： To investigate the pulmonary function of mild-to-moderate adolescent idiopathic scoliosis （AIS） pa- tients. Method： For this study, 68 AIS patients and 20 healthy subjects were recruited. Forced vital capacity （FVC）, FVC pred, FVC pred%, forced expiratory volume in first second （FEV1）, FEV1 pred, FEV1 pred%, and FEV1/FVC% of normal subjects and AIS patients were measured. Result： FEV1 pred% and FEV1/FVC% of AIS patients were （85.60±11.60） and （88.40±6.84）, meanwhile those of normal subjects were （93.20±9.39） and （91.00±3.13）. Compared with normal controls, AIS had lower FEVI pred% and FEV1/FVC%. No significant difference in FVC pred%, FEV1 pred% and FEV1/FVC% was found among different curve patterns and gender of AIS patients. There was a positive correlation between FVC, FVC pred, FEV1, FEV1 pred and age in AIS patients. However, there was no correlation between pulmonary function and Cobb angle in AIS patients. Conclusion： Mild-to-moderate AIS patients have pulmonary dysfunction generally. The pulmonary function has a positive correlation with the age, but no correlation with the curve pattern, gender and Cobb angle in mild-to- moderate AIS patients.

关 键 词：青少年 特发性 脊柱侧凸 肺功能 

分 类 号：R682.3[医药卫生—骨科学]