18-三体综合征胎儿孕早中期超声异常的临床分析  

Sonographic findings of trisomy 18 in the first and second trimester of pregnancy

作　　者：董兴盛[1] 欧德明[1] 陈咏莲[1] 李红艳[1] 王李洁[1] 江陵[1] 

机构地区：[1]广东省中山市博爱医院产前诊断中心,528403

出　　处：《中国优生与遗传杂志》2016年第7期93-94,101,F0002,共4页Chinese Journal of Birth Health & Heredity

基　　金：中山市科技计划项目[项目编号:中山科发[2015]170号2015SYF0104]

摘　　要：目的探讨18-三体综合征胎儿孕早中期超声异常声像特征。方法回顾性分析经细胞遗传学确诊的33例18-三体综合征胎儿产前超声异常声像。结果 33例18-三体综合征的胎儿产前超声检查均有2项及以上的超声异常。其中18例有心血管系统异常(54.5%),15例有中枢神经系统异常(45.5%),10例有骨骼系统异常(30.3%)。结论产前超声检查发现胎儿多系统的畸形,为产前筛查18-三体胎儿提供了重要临床线索。Objective：The purpose of this study was to examine the sonographic findings in fetuses with trisomy 18 in the first and second trimester of pregnancy. Methods：A retrospective review of prenatal sonographic studies of 33 cases of trisomy 18 fetal the identified by cytogenetic laboratory. Results：All cases had at least two abnormal sonographic findings. Cardiac（54.5%）,central nervous system（45.5%） and skeletal system（32.1%）anomalies were most frequently detected. Conclusions：Prenatal ultrasound examination can effectively screen effect fetus with trisomy 18.

关 键 词：产前超声 胎儿 18-三体综合征 

分 类 号：R445.1[医药卫生—影像医学与核医学] R714.5[医药卫生—诊断学]