T1期肺癌患者淋巴结转移特点及两种治疗方法的比较  

Characteristics of lymph node metastasis in T1 stage of lung cancer and comparison of two methods of treatment

作　　者：曹冠亚[1] 于在诚[1] 伍权[2] 

机构地区：[1]安徽医科大学第一附属医院胸外科,合肥230022 [2]安徽医科大学第四附属医院肿瘤科,合肥230000

出　　处：《重庆医学》2016年第20期2760-2762,共3页Chongqing medicine

基　　金：国家自然科学基金资助项目(81001046)

摘　　要：目的探讨T_1期肺癌淋巴结转移特点以及微创手术与开放手术的治疗效果比较。方法将120例T_1期肺癌手术患者分为两组,其中微创手术组68例,开放手术组52例,研究T_1期肺癌患者淋巴结转移数目,比较两种手术方法治疗不同大小肿瘤患者的围术期相关指标。结果患者均顺利完成手术,无手术死亡病例。两组在手术时间、术中出血量以及淋巴结清扫个数方面无明显差别。肿瘤最大直径小于或等于1.0cm、1.0~3.0cm患者的淋巴结转移率分别为1.3%、9.7%。肿瘤最大直径小于或等于1.0cm的鳞癌N1、N2均无转移。肿瘤最大直径小于或等于1.0cm的患者两种手术方式围术期相关临床指标差异有统计学意义(P<0.05),肿瘤最大直径1.0~3.0cm的患者围术期相关临床指标差异无统计学意义。结论肿瘤最大直径小于或等于1.0cm的T_1期肺癌患者更适合微创手术,但是肿瘤最大直径大于1.0cm的T_1期肺癌患者微创手术与开放手术的治疗效果无明显差异。Objective To investigate the characteristics of lymph node metastasis in T1 stage of lung cancer and the curative effects of minimally invasive surgery and open surgery. Methods Totally 120 cases of T1 stage of lung cancer were divided into two groups, 68 cases in the minimally invasive surgery group and 52 cases in the open surgery group, the number of lymph node metastasis in the patients with lung cancer in T1 stage were studied,the perioperative related indicators for different tumor size were compared between the two different surgical methods. Results All patients were successfully completed the operation without operative death case. The two groups had no significant difference in the aspects of operation time,intraoperative bleeding volume and number of lymph node dissection. The lymph node metastasis rates in the maximum tumor diameter ≤ 1.0,1.0- 3.0 cm were 1.3% and 9.7% respectively. N1 ,N2 squamous cancer of the maximal tumor diameter ≤1.0 cm had no metastasis. The perioperarive related clinical indicators in the maximal tumor diameter ≤1.0 cm had significant differences between the two kinds of operation method（P^0.05）, the periop-rative related clinical indicators in the maximal tumor diameter 1.0-3.0 cm had no significant differences between the two kinds of operation method. Conclusion The patients with T1 stage of lung cancer and the maximal tumor diameter≤1.0 cm are more suitable for the minimally invasive surgery, but the patients with T1 stage of lung cancer and the maximal tumor diameter〉1. 0 cm have little difference in minimally invasive surgery and open surgery.

关 键 词：肺肿瘤 淋巴结 胸腔镜手术 肺癌 开放手术 

分 类 号：R734.2[医药卫生—肿瘤]