阿胶改善甲襞微循环应用分析  

The Application Analysis of Colla Corii Asini on Improving Nailfold Microcirculation

作　　者：和娴娴[1] 汝文文[1] 钤莉妍[1] 卢艳[1] 刘腾腾[1] 王东亮[1] 

机构地区：[1]山东东阿阿胶股份有限公司国家胶类中药工程技术研究中心,山东聊城252201

出　　处：《中国药物评价》2016年第3期144-146,152,共4页Chinese Journal of Drug Evaluation

摘　　要：目的:观察分析阿胶改善甲襞微循环情况,以期为阿胶补血功效辨证提供借鉴。方法:300例中随机筛选出甲襞微循环非正常者试验组60例和对照组10例。试验组服用阿胶6 g·d^(-1),服用60 d,每15 d受试者检测1次甲襞微循环。结果:试验组受试者60例,改善46例,总有效率76.67%;对照组中仅有10%微循环积分存在改善。服用阿胶前受试者存在明显的甲襞微循环异常,经过服用阿胶后总积分明显降低,均表现出管袢数目和长度增加,输入枝增粗,血色变红,流速加快,畸形管袢数目减少等,并经统计学处理具有显著性差异(P<0.01)。结论:阿胶可明显改善甲襞微循环状态总积分,从而为阿胶补血功效辩证提供客观定量的指标。Objective： To observe and analyze Colla corii asini on improving the situation of total nailfold microcirculation,with a view to provide reference Colla corii asini blood effect syndrome. Methods： Screening abnormal nailfold microcirculation 300 cases,choose 60 cases as experimental group and 10 cases as control group at radom. Experimental group were taken Colla corii asini 60 d,6 g·d- 1,and they were detected nailfold microcirculation once every 15 d. Results： In the experimental group 60 cases,nailfold microcirculation of 46 cases were improved,total effective rate was 76. 67%; in the control group only 10% nailfold microcirculation was improved. Total score significantly decreased after taking Colla corii asini,the number of loops of pipe and length increased,input branches enlargemented,color redder,flow speed were improved,numbers of deformed tube loops were reduced etc,and which showed significant differences（ P 〈0. 01）. Conclusion： Colla corii asini can improve the total state of nailfold microcirculation integral significantly,which provide reference for modern research and clinical application.

关 键 词：阿胶 补血 甲襞微循环 

分 类 号：R285.6[医药卫生—中药学]