中西医结合治疗溃疡性结肠炎的效果观察  

Effect observation of integrated Chinese and Western medicines in treat-ing ulcerative colitis

作　　者：李榕萍[1] 

机构地区：[1]福州市第二医院消化内科,福州350007

出　　处：《中国当代医药》2016年第17期148-151,共4页China Modern Medicine

摘　　要：目的探讨中西医结合治疗溃疡性结肠炎的效果。方法选择我院2013年6月~2015年6月收治的溃疡性结肠炎患者60例,按照随机数字表法将其分为观察组（30例）和对照组（30例）。对照组给予西药柳氮磺胺吡啶联合雷尼替丁治疗,观察组在对照组的基础上给予中药煎剂口服、灌肠,观察两组的治疗效果。结果两组西医疗效比较：观察组和对照组的总有效率分别为90.0%和63.3%,组间比较,差异有统计学意义（P〈0.05）。两组中医证候疗效比较：观察组和对照组的总有效率分别为93.3%和63.3%,组间比较,差异有统计学意义（P〈0.05）。两组治疗后中医证候积分均明显降低,且观察组降低幅度更加明显,组间比较,差异有统计学意义（P〈0.05）。两组治疗前轻、中、重度病变比例,差异无统计学意义（P〉0.05）,治疗后观察组无重度病变患者,轻、中度病变比例也明显降低,与对照组比较,差异有统计学意义（P〈0.05）。两组治疗前白介素（IL）-6水平比较,差异无统计学意义（P〉0.05）,治疗后均有所改善,且观察组改善效果更加明显,组间比较,差异有统计学意义（P〈0.05）。结论西药柳氮磺胺吡啶、雷尼替丁配合中药煎剂口服、灌肠治疗溃疡性结肠炎效果满意。Objective To explore the effect of integrated Chinese and Western medicines in treating ulcerative colitis.Methods 60 ulcerative colitis patients from June 2013 to June 2015 of our hospital were selected and were divided into observation group（30 cases） and control group（30 cases） according to random number table.Patients in control group were given sulfasalazine combined with ranitidine.Patients in observation group were further given oral administration and enema traditional Chinese medicine apozem on the basis of control group.The treatment effects in two groups were observed.Results Western medicine curative effect compared in two groups,the total effective rate in observation group and control group was 90.00% and 63.3% respectively,and the difference was statistical significant（P〈0.05）.The Chinese medicine certificate waits curative effect compared in two groups,the total effective rate in observation group and control group was 93.3% and 63.3% respectively,and the difference was statistical significant（P〈0.05）.The TCM score in two groups decreased obviously after treatment,and the observation group was more obvious than control group,and the difference was statistical significant（P〈0.05）.Before treatment,the light,medium and severe lesions number between two groups had no obvious difference（P〉0.05）.After treatment,there was any severe lesions patients in observation group,and light,medium lesions number obvious decreased,which compared with control group,the difference was statistical significant（P〈0.05）.Before treatment,the IL-6 level between two groups had no obvious difference and improved after treatment（P〉0.05）,but the improvement effects in observation group were more obvious and the difference was statistical significant（P〈0.05）.Conclusion Western medicine sulfasalazine,ranitidine combined with oral administration and enema traditional Chinese medicine apozem with satisfactory effects in treating ulcerative colitis.

关 键 词：中西医结合 溃疡性结肠炎 中药 

分 类 号：R574.62[医药卫生—消化系统]