术前外周血单核细胞计数评估肾透明细胞癌患者预后的价值  

Value of preoperative monocyte counts in peripheral blood in evaluating prognosis of patients with renal clear cell carcinoma

作　　者：周文杰[1] 吴骏[1] 朱丽娜[1] 王琦[1] 吴昌平[1] 

机构地区：[1]苏州大学附属第三医院(常州市第一人民医院)肿瘤中心,江苏省213003

出　　处：《江苏医药》2016年第12期1381-1383,共3页Jiangsu Medical Journal

摘　　要：目的探讨术前外周血单核细胞计数评估肾透明细胞癌患者预后的价值。方法收集156例肾透明细胞癌患者的临床病理资料,分析术前外周血单核细胞计数和临床病理特征与患者生存预后之间的相关性。结果单因素分析显示,年龄、TNM分期、肿瘤坏死、脉管侵犯和单核细胞计数均与肾透明细胞癌患者预后相关(P<0.05或P<0.01)。多因素分析表明,单核细胞计数和TNM分期是肾透明细胞癌患者的独立预后因素(P<0.05)。结论术前外周血单核细胞计数与肾透明细胞癌患者的预后密切相关,可作为预测肾透明细胞癌患者预后的有用指标。Objective To investigate the value of preoperativemonocyte counts in peripheral blood in evaluating the prognosis of patients with renal clear cell carcinoma（RCCC）. Methods Clinical and pathological data of 156 patients with RCCC were collected and the correlation of monocyte counts and clinicopathological fetures with the prognosis were analyzed. Results Univariate analysis showed that age, TNM staging, tumor necrosis vascular invasion and monocyte count were significantly correlated to the prognosis（P〈0.05 or P〈0.01）. Multivariate analysis showed that the monocyte count and TNM staging were the independent factors to influence the prognosis（ P〈0. 05）. Conclusion The preoperative mononuclear cell count in peripheral blood is closely correlated to the prognosis of RCCC patients and may be taken as indicator in predicting the prognosis of RCCC patients.

关 键 词：肾透明细胞癌 单核细胞 

分 类 号：R737[医药卫生—肿瘤]