中晚期贲门癌锎-252中子腔内治疗的临床效果观察  

Clinical effect of 252 CF neutron endovascular treatment on advanced cardiac cancer

作　　者：贾喜堂 赵军 

机构地区：[1]山西省长治市人民医院肿瘤科,046000

出　　处：《中国实用医刊》2016年第13期60-62,共3页Chinese Journal of Practical Medicine

摘　　要：目的：观察中晚期贲门癌采用锎-252（^252 CF）中子腔内治疗的临床效果。方法采用随机抽样的方法选取2001年1月至2011年6月80例中晚期贲门癌患者，根据治疗方法将80例患者分为研究组（n＝40）和对照组（n＝40）。给予研究组患者^252CF中子腔内联合体外照射治疗，给予对照组患者单纯体外照射治疗。结果研究组患者吞咽困难Ⅰ级比例显著高于对照组（ P﹤0.05），Ⅲ级、Ⅳ级比例均显著低于对照组（ P﹤0.05），治疗的总有效率[92.5%（37/40）]显著高于对照组[60.0%（24/40），P ﹤0.05]，1、2、3年生存率均显著高于对照组（P ﹤0.05），恶心呕吐、吞咽困难、骨髓抑制等不良反应发生率均显著低于对照组（ P﹤0.05）。结论中晚期贲门癌采用252 CF中子腔内治疗的临床效果显著，值得推广。Objective To observe the clinical effect of ^252 CF neutron endovascular treatment on advanced cardiac cancer. Methods Eighty patients with advanced gastric cardiac cancer from January 2001 to June 2011 were selected by random sampling method,they were divided into study group（ n=40）and control group（n=40）according to the treatment methods. The patients in study group were given ^252 CF neutron endovascular combined with external beam treatment,while the patients in control group were given external beam therapy. Results The proportion of grade Ⅰdysphagia of the study group was significantly higher（ P﹤0.05 ）,the proportions of gradeⅢ,grade Ⅳ were significantly lower （P﹤0.05）,the total treatment efficiency was 92. 5%（37/40）,which was significantly higher than that of the control group[60. 0%（24/40）,P﹤0.05]. The 1 year,2 years,3 years survival rates were significantly higher（ P﹤0.05 ）,the incidences of nausea,vomiting,difficulty swallowing,bone＆amp;nbsp;marrow suppression and other adverse reactions were significantly lower than those of the control group （ P﹤0.05 ）. Conclusions The clinical effect of 252 CF neutron endovascular treatment on advanced car-diac cancer is significant,so it is worthy of promotion.

关 键 词：中晚期贲门癌 锎-252中子腔内治疗 临床效果 

分 类 号：R730.55[医药卫生—肿瘤]