经尿道双极等离子电切术治疗前列腺癌的临床效果  

Clinical research of transurethral bipolar plasma resection in the treatment of prostate cancer

作　　者：马玉生[1] 许孝新[1] 焦念辉[1] 李伟光[1] 张立刚[1] 

机构地区：[1]山东省临朐县人民医院泌尿外科,临朐262600

出　　处：《中国肿瘤临床与康复》2016年第7期842-845,共4页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的探讨经尿道双极等离子电切术治疗前列腺癌的临床疗效。方法选取2013年8月至2015年8月间山东省临朐县人民医院收治的80例前列腺癌患者,采取随机数字表法分为经尿道双极等离子电切术(TKRP)组和经尿道前列腺电切术(TURP)组,每组40例。比较两组患者的手术时间、术中出血量、尿管拔出时间、国际前列腺症状评分(IPSS)、最大尿流率、残余尿、血清前列腺特异性抗原(PSA)水平、并发症发生率和生活质量。结果 TKRP组与TURP组的手术时间差异无统计学意义(P>0.05)。TKRP组与TURP组间术中出血量减少、尿管拔出时间缩短间差异有统计学意义(P<0.05)。TKRP组与TURP组间治疗前IPSS评分、血清PSA、最大尿流率和残余尿量差异均无统计学意义(P>0.05)。与治疗前相比,治疗后TKRP组与TURP组患者IPSS评分降低、血清PSA水平降低、最大尿流率升高、残余尿量减少间差异有统计学意义(P<0.05);治疗后两组患者间差异无统计学意义(P>0.05)。与TURP组相比,术后TKRP组患者并发症发生率明显降低,组间差异有统计学意义(P<0.05);躯体功能、角色功能、情绪功能、认知功能、社会功能、总体健康状况评分均明显升高,差异有统计学意义(P<0.05)。结论采用TKRP治疗前列腺癌与TURP相比同样具有显著临床效果,TKRP可明显减少术中出血量、缩短尿管拔出时间、改善生活质量、并发症发生率较低,值得推广。Objective To explore the clinical research of transurethral bipolar plasma resection （TKRP） in the treatment of prostate cancer. Methods From August 2013 to August 2013 in Linqu County People＇s Hospital, 80 patients with prostate cancer were enrolled in the study and dividely randomly into TKRP group and transurethrue resection of prostate （TURP） group, 40 cases in each group. The operation time, intraoperative blood loss, urine tube pull out time, IPSS score, maximum urinary flow rate, residual urine and serum prostate-specific antigen （PSA） level and quality of life between the two groups were compared. Results The operation time between TURP group TKRP group showed no significant difference （ P 〉 0. 05 ）. Compared with TURP group, the intraoperative blood loss, urine tube pull out a shorter time in TKRP group showed significant diffferences （ P 〈 0. 05 ）. Compared with TURP group before therapy, International Prostate Symptom Score （IPSS） score, serum PSA, maximum urinary flow rate, residual urine volume in TKRP group showed no significant difference （ P 〉 0. 05 ）. After treatment, in both TKRP and TURP group, IPSS score was lower than, serum PSA levels dropped, the maximum urinary flow rate increased, residual urine volume decreased, with statistical significance （ P 〈 0. 05 ）. Compared before treatment in TURP group, the incidence of complications in TKRP group was significantly lower, with statistical significance （P 〈 0. 05 ） ; physical function, role function, emotional function, cognitive function, social function, and overall health score in TKRP group showed no significant difference （P 〈 0. 05 ） . Conclusions Using TKRP treatment for prostate cancer compared with TURP also has significant clinical efficacy, but can obviously reduce the intraoperative blood loss, shorten the urine tube pull out time, improve the quality of life. So it is worthy of clinical promotion.

关 键 词：前列腺肿瘤 经尿道双极等离子电切术 经尿道前列腺电切术 生活质量 

分 类 号：R737.25[医药卫生—肿瘤]