TACE联合RFA治疗膈下肝脏恶性肿瘤22例  

TACE combined with radiofrequency ablation for the treatment of malignant hepatic carcinomas located under the diaphragm:preliminary results in 22 patients

作　　者：庄少鹉[1] 刘明强[1] 刘丽莎[1] 

机构地区：[1]福建医科大学附属漳州市医院介入科,福建漳州363000

出　　处：《介入放射学杂志》2016年第7期595-597,共3页Journal of Interventional Radiology

摘　　要：目的 评价TACE联合RFA治疗膈下肝脏恶性肿瘤的安全性和疗效。方法 22例膈下肝脏恶性肿瘤患者共有26个病灶,单例病灶数目≤3个,直径≤5 cm。所有患者先行1-2次TACE术,术后3-5周行CT引导下RFA治疗,RFA术后4-8周复查MRI评价疗效。所有患者随访12-30个月,观察并发症和疗效。结果 22例患者26个病灶RFA术中未出现任何严重并发症,术后MRI复查22个（84.6%）病灶达到完全消融,4个（15.4%）病灶经2次RFA后达到完全消融。结论 TACE术可使肝脏恶性肿瘤病灶缩小,轮廓更加清晰,联合RFA治疗膈下肝脏恶性肿瘤更加安全、精确、有效。Objective To evaluate the safety and efficacy of the transcatheter arterial chemoembolization （TACE） combined with radiofrequency ablation （ RFA ） in treating malignant hepatic carcinomas located under the diaphragm. Methods Twenty-two patients with malignant hepatic carcinoma located under the diaphragm were included in this study. A total of 26 lesions were detected, the number of lesions was less than 3 in a single patient, and the maximum diameter of lesion was ≤ 5 cm. One or two times of TACE were carried out first in all patients, which was followed by CT-gnided RFA in 3-5 weeks after TACE. MRI reexamination was performed in 4-8 weeks after RFA to evaluate the therapeutic effect. All patients were followed up for 12-30 months for the observation of complications and therapeutic effect. Results No severe complications occurred during RFA in treating all 26 lesions of 22 patients. Postoperative MRI reexamination showed that complete ablation was obtained in 22 lesions （ 84.6% ）, and in 4 lesions complete ablation was achieved after 2 times of RFA. Conclusion TACE can diminish the size of malignant hepatic lesions, make the outline of the lesion more clearly. In treating malignant hepatic carcinomas located under the diaphragm, TACE combined with RFA is safer, more accurate and more effective.

关 键 词：经导管动脉化疗栓塞术 肝脏恶性肿瘤 射频消融 

分 类 号：R735.7[医药卫生—肿瘤]