电视胸腔镜与传统手术对治疗非小细胞肺癌患者心肺功能影响分析  

The comparison of VATS and traditional surgery in the influence of cardiopulmonary function of non- small cell lung cancer patients

作　　者：杨欣[1] 曾兴建[1] 付娟[1] 

机构地区：[1]三峡大学第二人民医院暨宜昌市第二人民医院胸外科,湖北宜昌443000

出　　处：《临床和实验医学杂志》2016年第11期1087-1089,共3页Journal of Clinical and Experimental Medicine

摘　　要：目的研究电视胸腔镜手术与传统手术相比治疗非小细胞肺癌患者对其心肺功能的影响。方法选取2013年1月至2015年1月接受治疗的82例非小细胞肺癌患者,将其分为两组,观察组(41例)和对照组(41例)。观察组采用电视胸腔镜下手术,对照组采用传统手术方式开胸。观察两组患者手术前后肺功能指标[用力肺活量(FVC)、用力呼气容积1 s(FEV1.0),最大自主通气量(MVV)],术后第1、4周2患者心功能指标[心率(HR)、左室射血分数(LVEF)、脉搏量(SV)]以及两组患者心肺并发症发生率。结果通过对两组患者手术前后肺功能常用指标比较可知,观察组术后4周FVC、FEV1、MVV值分别为(1.61±0.31)、(1.43±0.21)、(54.82±11.58),较术后1周均有所升高,差异具有统计学意义(P<0.05)。观察组术后1周、4周FVC、FEV1、MVV均高于对照组,差异具有统计学意义(P<0.05);通过两组患者术后1周、4周心脏功能的比较发现,观察组术后4周HR、SV、LVEF值分别为(67.21±8.14)、(68.13±9.46)、(59.61±5.11),较术后1周值(72.8±8.46)、(63.44±9.57)、(54.63±5.21)均有所升高,差异具有统计学意义(P<0.05)。观察组术后1周、4周HR、SV、LVEF均高于对照组,差异具有统计学意义(P<0.05);观察组并发症发生率为7.3%(9/41),明显低于对照组并发症发生率26.8%(26/41),两组比较差异具有统计学意义(P<0.05)。结论与传统手术相比,电视胸腔镜手术对患者创伤小,可以减少患者心肺功能并发症的发生,有效地改善患者的心肺功能。Objective To compare the impact of video - assisted thoracoscopic surgery and traditional surgery in cardiopulmonary func-tion in patients with non - small cell lung cancer. Methods 82 patients with non - small cell lung cancer,from January 2013 to January 2015 in our hospital,were divided into two groups,Observation group（41 cases）and control group（41 cases）. Observation group performed VATS sur-gery and control group performed traditional surgical thoracotomy. Lung function indicators before and after surgery were observed. The cardiac function indicators 1 and 4 weeks after surgery were observed. The cardiopulmonary complication rate in the two groups were also reviewed. Re-sults The pulmonary function indicators after 4 weeks were increased the those after 1 week,FVC,FEV1,MVV values were（1. 61 ± 0. 31）, （1. 43 ± 0. 21）,（54. 82 ± 11. 58）. And the difference was statistically significant（ P 〈 0. 05）. FVC,FEV1,MVV in observation group after one week,four weeks were higher than those control group,the difference was statistically significant（ P 〈 0. 05）;The cardiac function indicators after 4 weeks,HR,SV,LVEF values were（67. 21 ± 8. 14）,（68. 13 ± 9. 46）,（59. 61 ± 5. 11）,were increased the those after 1 week,HR, SV,LVEF values were（72. 8 ± 8. 46）,（63. 44 ± 9. 57）,（54. 63 ± 5. 21）. And the difference was statistically significant（ P 〈 0. 05）. HR, SV,LVEF in observation group after one week,four weeks were higher than those control group,the difference was statistically significant（ P 〈0. 05）;The complication rate in observation group was 7. 3% ,is lower than that in control group（26. 8% ）. The difference was statistically sig-nificant（ P 〈 0. 05）. Conclusion Compared with traditional surgery,VATS on non - small cell lung cancer patients,can reduce the incidence of complications in patients with heart and lung function,effectively improve the patient′s heart and lung function.

关 键 词：非小细胞肺癌 电视胸腔镜 传统开胸手术 心肺功能 

分 类 号：R734.2[医药卫生—肿瘤]