功能性消化不良患者的社会人口学特征与精神心理状况的研究  

Analysis of social demographic characteristics and mental disorder of functional dyspepsia

作　　者：王慧芬[1,2] 姚树坤[1,2] 杜时雨[1] 刘芳[1,2] 王淼[1] 张艳丽[1] 

机构地区：[1]中日友好医院消化内科,北京100029 [2]中国医学科学院北京协和医学院研究生院

出　　处：《胃肠病学和肝病学杂志》2016年第7期791-795,共5页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的 观察功能性消化不良（functional dyspepsia,FD）患者的社会人口学特征,比较不同人口学特征组的FD患者的精神心理状况。方法 对中日友好医院消化内科门诊就诊的273例FD患者进行人口学特点统计,采用Zung氏焦虑/抑郁自评量表（SAS/SDS）评价精神心理状态。结果 （1）在FD疾病症状谱方面,餐后饱胀在FD患者中发生比例最高,其次为嗳气及早饱。FD症状评分中可见餐后饱胀评分最高,其次为上腹痛、早饱和嗳气。（2）精神心理状况评价：女性与男性相比,SAS评分更高（46.47±10.33 vs 43.43±9.33,P=0.020）。年龄在50~59岁的FD患者SAS评分明显高于年龄〈30岁的患者（48.22±10.57 vs 42.88±11.56,P=0.039）;前者的SDS评分也显著高于后者（0.54±0.11 vs 0.46±0.11,P=0.001）。离异或丧偶患者SAS评分及SDS均明显高于已婚患者（P=0.001）。大学本科以上文化程度FD患者SAS评分明显低于初中以下的患者（40.40±10.68 vs 48.47±11.20,P=0.001）。FD的不同亚组之间进行比较发现,EPS组和PDS组之间的SAS评分及SDS评分差异无统计学意义（P〉0.05）。EPS＋PDS组的SAS评分显著高于PDS组及EPS组（P=0.001）,SDS评分显著高于单纯EPS组（P=0.004）。（3）FD症状与精神心理的相关性：上腹痛与SAS、SDS,上腹烧灼感与SAS,早饱感与SDS,呕吐与SAS,嗳气与SAS、SDS均存在直线相关,均呈正相关。结论 本研究资料来自一家三级综合医院,不同的人口学特征的FD患者的精神心理状态可能不同,其中女性患者、离异或丧偶患者和中年患者的SAS、SDS评分较高,而高学历患者的SAS、SDS评分较低。FD症状与SAS、SDS情绪有相关性,症状越重,SAS、SDS评分越高。Objective To investigate the social demographic characteristics of patients with functional dyspepsia （FD） and the mental disorder of different types patients with FD. Methods Self-rating anxiety scale （SAS）, self-rat- ing despression scale （SDS） and social demographic characteristics were recorded in 273 patients with FD. Results （1） Postprandial fullness was the most predominant symptom in patients of FD, followed by epigastric distention. The score of postprandial fullness was the highest in the score of FD, followed by epigastric pain, satiety, belching. （2） There was significant difference in SAS between females and males （46.47 ± 10.33 vs 43.43 ±9.33, P =0. 020）. The SAS score of 50 - 59 years old patients was significantly higher than the patients who were 〈 30 years old （48.22 ± 10.57 vs 42.88 ± 11.56, P = 0. 039）. There were significant differences in SDS index in 50 -59 years old patients group compared with 〈 30 years old patients （0.54 ＋ 0.11 vs 0.46 ± 0. 11, P = 0. 001 ）. There was significant difference in SAS score and SDS index in divorced patients group compared with married patients group （51.50 ＋ 11.69 vs 41.23±11.48, P=0.001; 0.54±0.13 vsO. 45±0. 11, P=0.001）. The SAS score of scholar degree patients was lower than that of junior high school patients （40.40 ± 10.68 vs 48.47 ± 11.20, P = 0. 001 ）. （3） Correlation between FD symptoms and mental psychology： upper abdominal pain was related with SAS and SDS. Epigastric burning sensation was related with SAS. Satiety was related with SDS. Vomitting was related with SAS. Belching was related with SAS and SDS. Conclusion The paper revealed that significant different mental status in patients with FD. There are high scores with SAS and SDS in patients with middle-age, women and divorced patients. There are low scores with SAS and SDS in patients with highly educated patients.

关 键 词：功能性消化不良 社会人口学特征 焦虑 抑郁 

分 类 号：R574.4[医药卫生—消化系统]