胆南星质量标准的现状与思考  

Current Situation and Discussion of Quality Standards of Arisaema Cum Bile

作　　者：李欣逸 解达帅 胥敏[1] 刘玉杰[1] 李明鉴[1] 艾莉[1] 吴纯洁[1] 

机构地区：[1]成都中医药大学,成都611137

出　　处：《中国实验方剂学杂志》2016年第14期231-234,共4页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：胆南星是常用的清热化痰、息风定惊药,但目前胆南星的质量标准简单粗略,尚不规范,无相关的制法、检查、含量测定等内容。《中国药典》2015年版中仅有简单描述——本品为制天南星的细粉与牛、羊或猪胆汁经加工而成,或为生天南星细粉与牛、羊或猪胆汁经发酵加工而成。导致厂家生产胆南星制法不一,质量参差不齐,不利于胆南星的质量监控,并影响其临床用药的安全性和有效性。通过对胆南星文献研究进行归纳并结合对生产企业实地调研,本文针对目前胆南星及其炮制辅料质量标准存在的主要问题,提出相应对策与建议,建议增加相应检测指标并完善辅料标准等,有助于规范和完善胆南星及其炮制辅料的质量标准,供同行思考与借鉴。Arisaema Cum Bile is usually used in dissipating phlegm, dispelling wind and relieving convulsion. Now there are no relevant method, examination and content determination of quality standards of Arisaema Cum Bile. In the 2015 edition of Chinese Pharmacopoeia, only brief process description of Arisaema Cum Bile exists, which lead to varying quality with different manufacturers and go against development of quality standardization, and it will influence safety and effectiveness of clinical medication. Through literature survey and field research, aiming at main problems of quality standards of Arisaema Cum Bile and its process auxiliary material, we put forward corresponding suggestions and references for colleague which help to regulate and improve its quality standards.

关 键 词：胆南星 质量标准 发酵 胆汁 猪去氧胆酸 胆酸 

分 类 号：R284.1[医药卫生—中药学] R283.2[医药卫生—中医学]