扶正升白汤治疗乳腺癌术后化疗不良反应的临床效果观察  

Observation on the clinical effect of Fuzhengshengbai decoction in treatment of adverse reactions of chemotherapy after breast cancer surgery

作　　者：董万斌[1] 席江伟[1] 刘斌[1] 苏心镜[1] 

机构地区：[1]河北北方学院附属第二医院,河北宣化075100

出　　处：《中国妇幼保健》2016年第14期2827-2829,共3页Maternal and Child Health Care of China

摘　　要：目的探讨扶正升白汤在防治乳腺癌术后化疗所致血液学毒性及胃肠道反应方面的临床效果。方法共纳入乳腺癌术后患者56例随机分为观察组和对照组各28例,在术后化疗期间,观察组予服用扶正升白汤,对照组口服鲨肝醇,观察两组患者血液学水平变化及胃肠道反应情况。结果观察组在化疗期间白细胞、血小板计数及血红蛋白下降程度较对照组明显减轻,差异有统计学意义(P<0.05);两组在胃肠道反应方面(恶心与呕吐程度评分水平)差异有统计学意义(P<0.05)。结论扶正升白汤能明显减轻乳腺癌患者化疗期间血液学毒性及胃肠道反应。Objective To explore the clinical effect of Fuzhengshengbai decoction in prevention and treatment of hematological toxicity and gastrointestinal reactions induced by chemotherapy after breast cancer surgery.Methods Fifty-six breast cancer patients after surgery were selected and randomly divided into control group and observation group,28 patients in each group.During postoperative chemotherapy,the patients in observation group were treated by Fuzhengshengbai decoction,while the patients in control group were treated by oraled batilol.The changes of hematological levels and gastrointestinal reactions were observed.Results The decreasing degrees of white blood cells,platelet count,and hemoglobin during chemotherapy in observation group were statistically significantly lighter than those in control group（ P〈0.05）.There was statistically significant difference in gastrointestinal reactions（ scores of nausea and vomiting） between the two groups（ P〈0.05）.Conclusion Fuzhengshengbai decoction can significantly relieve hematological toxicity and gastrointestinal reactions during chemotherapy in breast cancer patients after surgery.

关 键 词：扶正升白汤 乳腺癌 化疗 血液学毒性 胃肠道反应 

分 类 号：R737.9[医药卫生—肿瘤]