乳腺癌患者E-cad表达对MRI影像特点的影响分析  

Effect of E-cad Expression in Patients with Breast Cancer on MRI Findings

作　　者：蔡伶伶[1] 杜光烨[1] 王博成[1] 赵江民[1] 

机构地区：[1]上海交通大学医学院附属第九人民医院放射科,上海201999

出　　处：《中国CT和MRI杂志》2016年第8期48-50,共3页Chinese Journal of CT and MRI

基　　金：上海市第三人民医院院基金项目syz2014-009

摘　　要：目的总结乳腺癌患者E-cad表达对MRI影像特点的影响。方法选取我院2012年3月-2015年12月收治86例乳腺癌患者为例,均行MRI、免疫组化检查,比较E-cad阳性及阴性患者MRI影像表现的差异。结果 60例E-cad阳性表达患者中,16例(26.7%)形状为类圆形、60.0%(36/60)边缘为光滑或毛刺、36.7%(22/60)为均匀与环形强化、48.3%(29/60)为TIC I型与Ⅱ型曲线,所占比例均高于E-cad阴性表达患者,差异有统计学意义(P<0.05)。结论乳腺癌患者E-cad阳性表达者形状多为类圆形、边缘光滑或有毛刺、均匀或环形强化,TIC曲线以I型与Ⅱ型居多,影像表现与E-cad阴性表达患者存在较大差异。Objective To summarize the effect of E-cad expression on MRI imaging characteristics of breast cancer patients.Methods A total of 86 cases of patients with breast cancer who were treated in our hospital between March 2012 and December 2015 were selected as subjects. All patients were examined by MRI and immunohistochemistry. The differences of MRI findings between positive and negative expression of E-cad were analyzed.Results Among the findings of 60 patients with positive expression of E-cad, 16 cases （26.7%） showed quasi-circular shape, 60% （36/60） showed smooth or burr edges, 36.7% （22/60） showed homogeneous and ring enhancement and 48.3% （29/60） showed TIC I and II type curve. The proportions were higher than those in patients with negative expression of E-cad （P〈0.05）.Conclusion The findings of patients with breast cancer and positive expression of E-cad are quasi-circular, with smooth or burr edges, homogeneous or ring enhancement. The major curves are type I and II. The imaging findings are significantly different from those of patients with negative expression of E-cad.

关 键 词：乳腺癌 E-CAD表达 MRI 影像表现 

分 类 号：R737.9[医药卫生—肿瘤] R445.2[医药卫生—临床医学]