生物催化绿色制造精细化学品进展与实例  

Development and Case Study of Biocatalysis Based Green Chemistry in Fine Chemical Manufacture

作　　者：陶荣盛[1] 范文超[1] 朱傅赟[1] 原犇犇[2] 姜卫红[2] 杨蕴刘[2] 蒋宇[1,2,3] 杨晟[1,2,3] 

机构地区：[1]中国科学院上海生命科学研究院湖州工业生物技术中心,浙江湖州313000 [2]中国科学院上海生命科学研究院,上海200032 [3]上海工业生物技术研发中心,上海201201

出　　处：《上海应用技术学院学报（自然科学版）》2016年第2期103-111,共9页Journal of Shanghai Institute of Technology: Natural Science

基　　金：国家重点基础研究发展计划(973计划)资助项目(2014CB745101);国家高技术研究发展计划(863计划)资助项目(2015AA021004);中国科学院科技服务网络计划(STS计划)资助项目(KFJ-EW-STS-030);上海优秀技术带头人资助项目(14XD1424900)

摘　　要：生物催化是精细化工增效减排的重要手段.基因组数据库和DNA合成技术的发展降低了生物催化酶的开发成本,使得近年来生物催化应用大大提速.以中科院上海生命科学院参与的相关项目为主,综述了国内近十多年来的生物催化在精细化工领域的应用实例,并讨论了生物催化面临的机遇与挑战.Biocatalysis is an important means for energy saving and emission reduction in fine chemical industry.The development of genome database and DNA synthesis technology in recent years has greatly reduced RD cost of biocatalysts enzymes,enabling the widespread application of biocatalysis.The relevant projects undertaken by Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences were taken as main examples,the application examples of biocatalysis in the field of fine chemical industry in recent 10 years in China were reviewed,and the opportunities and challenges facing biocatalysis were discussed as well.

关 键 词：生物催化 绿色制造 精细化学品 酶工程 

分 类 号：TQ06[化学工程]