急性脱髓鞘脑病的临床症状表现与诊治研究  

Clinical manifestation and research of diagnosis and treatment of acute demyelinating encephalopathy

作　　者：于振江[1] 芦朋[2] 

机构地区：[1]山东莱芜钢铁集团有限公司医院神经内科 [2]山东莱芜钢铁集团有限公司医院五官科

出　　处：《中国实用医药》2016年第15期19-20,共2页China Practical Medicine

摘　　要：目的研究并总结急性脱髓鞘脑病的临床症状和典型表现,总结临床诊断急性脱髓鞘脑病的标准和治疗方案。方法 32例急性脱髓鞘脑病患者为研究对象,回顾性分析其临床症状,总结诊断标准。入院后根据患者家属治疗意愿将32例患者分为研究组和对照组,各16例,对照组使用地塞米松治疗,研究组使用甲泼尼龙治疗,比较两组治疗效果。结果研究组临床总有效率93.75%高于对照组62.50%,差异具有统计学意义(P<0.05)。结论患者发生癫痫、呕吐等神经系统症状,合并脑电图和脑脊液检查结果异常,要考虑发生急性脱髓鞘脑病,使用甲泼尼龙治疗急性脱髓鞘脑病临床疗效显著。ObjectiveTo research and summarize clinical symptoms and manifestation of acute demyelinating encephalopathy, and to summarize its clinical diagnostic standard and treatment strategy.MethodsA retrospective analysis was made on clinical symptoms of 32 acute demyelinating encephalopathy patients to summarize their diagnostic standard. The 32 patients were divided into research group and control group, with 16 cases in each group. The control group received dexamethasone, and the research group received methylprednisolone. Curative effects of the two groups were compared.ResultsThe research group had higher total effective rate as 93.75% than 62.50% of the control group, and their difference had statistical significance （P〈0.05）.ConclusionEpilepsy and emesis complicating with abnormal electroencephalogram and cerebrospinal fluid examination requires consideration of acute demyelinating encephalopathy. Implement of methylprednisolone provides precisely clinical effect in treating acute demyelinating encephalopathy.

关 键 词：急性脱髓鞘脑病 临床症状 诊断 治疗 

分 类 号：R744.5[医药卫生—神经病学与精神病学]