子宫非典型性息肉样腺肌瘤6例临床病理分析  

Clinicopathological features of uterine atypical polypoid adenomyoma

作　　者：赵燕[1] 刘福兴[1] 卢婷[1] 叶军[2] 

机构地区：[1]泰州市人民医院病理科,江苏泰州225300 [2]泰州市人民医院中心实验室,江苏泰州225300

出　　处：《诊断病理学杂志》2016年第7期496-498,503,共4页Chinese Journal of Diagnostic Pathology

基　　金：江苏省卫生厅科技发展基金项目(201456)

摘　　要：目的探讨子宫非典型性息肉样腺肌瘤（APA）。方法收集和观察6例子宫非典型性息肉样腺肌瘤的临床病理特点，并复习文献。结果6例患者年龄33—53岁，平均43．5岁。主诉月经量增多、阴道异常出血，B超检查偶然发现。肿瘤最大径2～5cm，平均2．6cm。3例位于子宫体部，1例位于子宫下段，2例位于子宫底部。肿瘤形态主要表现为复杂的分支腺管状结构，4例见鳞化，2例见腺腔内红染颗粒样坏死物。1例癌变为高分化子宫内膜样腺癌。随访时间1～36个月，未见复发。结论子宫内膜非典型性息肉样腺肌瘤多数临床经过良好，少数APA进展为子宫内膜样腺癌。Objective To study the characteristics of uterine atypical polypoid adenomyoma （APA）. Methods The clinicopathologic features were retrospectively reviewed in 6 cases of APA. Results The 6 patients aged from 33 to 53 years （mean = 43.5 years ）. The patients had menstrual quantity increase, irregular vaginal bleeding, contact hemorrhages or accidental discovery by ultrasound examination. The tumor maximum diameter varied from 2. 0 to 5.0 cm （ mean = 2. 6 em）. Three cases were located in the body of the uterus. Two cases were located at the bottom of the uterus. Another one was located in the lower uterine segment. The tumor had very complex branching structure of glands. Squamous metaplasia was present in 4 cases. Mucus and necrosis were seen in the glandular cavity in 2 cases. 1 case was transformed to grade 1 endometrioid adenocarcinoma. The patients had no signs of tumor recurrence after follow - up for time range from 1 to 36 months. Conclusion The tumors of APA generally have benign clinical courses. A few cases of APA may progress to endometrioid adenocarcinoma.

关 键 词：非典型性息肉样腺肌瘤 子宫 分子病理学 

分 类 号：R737.33[医药卫生—肿瘤]