高原建设者维生素D水平的影响因素调查研究  

Study on the Influence Factors of Vitamin D Level in Plateau Builder

作　　者：何清华[1] 周晓梅[1] 陈德才[2] 朱可[1] 唐晨[1] 高学明[1] 

机构地区：[1]四川电力医院内科,四川成都610021 [2]四川大学华西医院内分泌科,四川成都610041

出　　处：《四川医学》2016年第7期721-725,共5页Sichuan Medical Journal

基　　金：成都市卫生局科研基金(编号:2014090)

摘　　要：目的研究川藏高原某单位建设者的维生素D水平及其影响因素。方法采用随机分层整群抽样方式,抽取四川甘孜州巴塘县、西藏芒康县境内从事某建设人群共650份血液标本,采用酶联免疫法进行血清25（OH）D_3的检测。选择25（OH）D_3〈50 nmol/L、50~75nmol/L和75~150 nmol/L的不同测定值定义维生素D为缺乏、不足、适宜,分析不同海拔地区建设者维生素D水平,探索其影响因素。结果 650例高原建设者年龄18~67岁,平均年龄（37.77±11.04）岁,男574例,女76例,血清25（OH）D_3平均值为（64.10±19.10）nmol/L,PTH（37.08±18.88）pg/m L,呈近似正态分布。维生素D缺乏者24.9%,不足者47.5%,适宜者27.6%。不同海拔地区的建设者血清25（OH）D_3平均值差异有统计学意义（P〈0.05）。结论高原藏区建设者维生素D水平总体偏低,但缺乏者仅24.9%,较其它地区人群维生素D营养状况好,这与高原特殊环境及建设者较长户外活动时间有关。Objective To study the level of vitamin D and its influence factors on Sichuan Tibet Plateau builders. Methods 650 cases of builder from Batang County in Sichuan province and Mangkang County in Tibet were detected the with ELISA by stratified sampling. The level of serum-25（ OH） D3 were defined as deficiency（ 50nmol / L）,insufficient（ 50 ~ 75 nmol / L） and normal（ 75 ~ 150 nmol / L）,which was used to analyze to level of vitamin of builders at different altitudes and to explore the influence factors. Results The distribution of serum-25（ OH） D3（ 64. 10±19. 10nmol/L） and PTH（ 37. 08 ±18. 88pg/ml） of 650 plateau builder,aged from 18 ~ 67 years（ 37. 77±11. 04）,with 574 males and 76 females,was a normal distribution. There were 24. 9% of vitamin D deficient,47. 5% of vitamin D insufficient and 27. 6% of vitamin D suitable. The mean values of serum-25（ 0H） D3 were statistically significant（ P〈0. 05） at different altitudes. Conclusion The level of vitamin D of Plateau Tibetan builders was generally low but with only 24. 9% deficiency,which was better than those in other regions,due to the special environment of Plateau Tibetan and long outdoor hours.

关 键 词：维生素D 高原停留时间 海拔高度 

分 类 号：R151.41[医药卫生—营养与食品卫生学]