基于电解反应的便携式微流体泵送装置设计及其性能研究  

A portable microfluidic pump design based on electrolytic reaction and property researches

作　　者：闫姿姿 李姗姗[1,2] 李铭浩[1] 张明航[1] 李铁军[1,2] 戴士杰[1,2] 

机构地区：[1]河北工业大学机械工程学院,天津300130 [2]河北工业大学机器人自动化研究所,天津300130

出　　处：《河北工业大学学报》2016年第3期9-15,共7页Journal of Hebei University of Technology

基　　金：国家自然科学基金(51505123);河北省自然科学基金(E2013202228);河北省高等学校青年拔尖人才计划项目(BJ2014014);中国博士后科学基金(M5980190);河北省重点研发计划自筹项目(15271704);河北工业大学引进人才科研启动经费(208003);河北省研究生优秀创新课题(220056)

摘　　要：微流体的进样和高效泵送是微流控芯片技术实现其功能的基础，目前多采用微流体注射泵实现对微量流体的输送，但与微流控芯片相比，泵体体积较大，且难于与芯片集成．本文基于电解食盐水原理，设计并开发了一种廉价的便携式微流体泵送装置，通过直流电源电解生成的气相流体产生的压力驱动2种液相流体流动，实现了对微流体的可控泵送．微泵主体结构由3D打印而成，用于微泵性能测试的PDMS微流控芯片则利用软光刻工艺加工，体积仅为数立方厘米．在5～10V直流电压的驱动下，可实现4～12μL／min的流量，且流量与电压呈近似线性关系．利用该装置，在自主设计、加工并封装的液滴生成微流控芯片中生成了均匀的液滴，验证了该装置在微流体泵送过程中的可靠性．Sample injection and efficient pumping is the basis ofmicrofluidic to realize its functions. Recently microfluidic injection pump is mostly used as the energy source to convey fluids, but the volume of the injection pump is huge compared with microfluidic chips, and it is hard to integrate with the microfluidic chips. In this paper, a cheap and portable micropump was developed based on the principle of electrolytic saturated salt water, DC power was used as the energy source, the generated gases can drive the fluids in different cavities flow to different channels, then controlled pumping can be realized. The main body structure of the micropump is made by 3D printing, the microfluidic chips used to test the performance of the micropump is made by soft lithography, and the volume of the microfluidic chip is in cubic centimeter. The voltage used in the experiment is among 5 - 10 V and the flow rate can reach 4 - 12 μL/min, which is approximately linearly related to voltages. Then droplets are generated in independence design and encapsulated microfluidic chips using this microfluidic pump, thus the reliability of the device has been verified.

关 键 词：微流控 微流体泵送 便携 电解 液滴生成 

分 类 号：O651[理学—分析化学]