AH plus与氧化锌丁香油糊剂根尖封闭性能对比的Meta分析  

Performance comparison of AH plus and zinc oxide clove oil paste root tip seal：a Meta-analysis

作　　者：周倩妹[1] 李秀娥[1] 张琳[1] 严红[1] 刘玲[1] 吴君[1] 

机构地区：[1]北京大学口腔医院护理部,100081

出　　处：《中华现代护理杂志》2016年第4期531-536,共6页Chinese Journal of Modern Nursing

摘　　要：目的：对比评价根管充填糊剂AH plus和氧化锌丁香油的根管封闭性能。方法计算机检索PubMed、CNKI及Cochrane图书馆临床对照试验数据库等,查找符合纳入标准的随机对照试验,文献检索时间均从建库截至2014年10月20日。并按Cochrane系统评价手册的文献质量评价办法评价纳入研究的方法学质量,而后提取相关数据用RevMan 5.1软件进行Meta分析。结果最终纳入23篇随机对照试验,共4104个患牙。 AH plus糊剂组的治疗后疼痛发生率低于对照组,两组比较差异有统计意义[OR=0.32,95%CI（0.26,0.39）,P〈0.01]。干预1-2年后,AH plus糊剂组的治愈率高于对照组,两组比较差异有统计学意义[OR=2.61,95%CI（2.03,3.35）,P〈0.01]。树脂类根管充填糊剂AH plus的根尖微渗漏长度优于对照组,差异有统计学意义[MD=-1.28,95%CI（-1.48,-1.08）,P〈0.01]；印度墨水溶液染色法测量患牙的渗透长度,差异有统计学意义[MD=-0.82,95%CI（-0.90,-0.74）,P〈0.01]。结论 AH plus糊剂在根管治疗中可以缓解患者疼痛,远期疗效好,生物相容性较好,是理想的根管充填材料。由于纳入分析的研究质量差异较大,因此有必要进一步开展大样本、多中心、随机、双盲的对照试验。Objective To comparative evaluation of root canal filling paste AH-plus and zinc oxide root canal of clove oil seal performance. Methods By computer, we retrieved PubMed, CNKI and controlled clinical trial databases to find out the standard randomised controlled trial, and literature retrieval time from building library until October 20, 2014. According to the Cochrane literature quality evaluation method of system for the evaluating methodlogical quality of the study, and then we extracted the relevant data and analyzed by Rev Man 5. 1 software for Meta analysis. Results Eventually the study included in 23 articles of randomized controlled trials, and a total of 4104 teeth. The results showed the pain occurred after plus treatment of AH paste group which was lower than that in the control group [OR=0. 32, 95%CI（0. 26,0. 26）, P〈0. 01）;AH plus paste group cure rate was higher than that of the control group after intervened 1 -2 years [ OR=2. 61, 95%CI（2. 03, 2. 03）, P〈0. 01];the paste resin class root filling AH plus length of root tip leakage was better than that of the control group, and nail polish and wax experiment method of measuring the penetration length of the tooth had statistical significance [MD=1. 28,95%CI（ -1. 48,-1. 08）, P〈0. 01]; India ink staining solution to measure the penetration length of the tooth had statistical significance [MD=0. 82, 95% CI（-0. 90,-0. 74）,P〈0. 01]. Conclusions AH plus paste in root canal therapy can significantly alleviate pain, and the long-term curative effect is good, and better than biological intermiscibility, which is an ideal root canal filling material. Due to large incorporated in the analysis of the research and the quality difference, it is necessary for large sample, multicenter, randomized, double-blind, placebo-controlled trails to further confirm the clinical curative effect.

关 键 词：META分析 AH plus糊剂 氧化锌丁香油糊剂 根尖封闭性能 

分 类 号：R781.05[医药卫生—口腔医学]