Venlafaxine Dependence： A Case Report  

作　　者：Ugur Cikrikcili Gasim Gasimzada Ilhan Yargic 

机构地区：[1]Department of Psychiatry, Istanbul Faculty of Medicine, University of lstanbul, lstanbul 34093, Turkey

出　　处：《Journal of Pharmacy and Pharmacology》2016年第8期378-380,共3页药剂与药理学（英文版）

摘　　要：Venlafaxine, an SNRI （serotonin-norepinephrine reuptake inhibitor） drug, is commonly used to treat depression. Although it is very rare, venlafaxine may lead to addiction or abuse in some patients. To date, there are very limited data available on venlafaxine addiction. The aim of this article is to draw an attention to dependence of venlafaxine in clinical practice. Significant point of this article is： Our patient was addicted by ＂high＂ doses of venlafaxine for getting high effects. Overdose of venlafaxine produces an amphethamine-like ＂high＂ with experiences of euphoria by its ability to increase neurotransmitter levels in addiction literature [1-3]. We present a man aged 42 years, who was referred to our clinic for detoxification from venlafaxine addiction. He had been taking venlafaxine upto 1,950-2,100 mg/day to get high for the past 10 years. Physicians must be careful when prescribing antidepressants to patients, especially those with a history of alcohol and/or drug addictions or abuse.

关 键 词：ADDICTION DEPENDENCE ANTIDEPRESSANT venlafaxine. 

分 类 号：Q577[生物学—生物化学] Q425