乳腺颗粒细胞瘤诊治进展  

Granular cell tumor of the breast： progress of diagnosis and therapy

作　　者：刘锋[1] 甘露[2] 杨得娟 李洪忠 任国胜[1] 

机构地区：[1]重庆医科大学附属第一医院内分泌乳腺外科,重庆400016 [2]重庆医科大学附属第一医院肿瘤内科,重庆400016 [3]分子肿瘤及表观遗传学重庆市重点实验室,重庆400016

出　　处：《中国医师杂志》2016年第7期1108-1111,共4页Journal of Chinese Physician

基　　金：科技部国际科技合作项目（2012DFA10650）;科技部863计划子课题（2012AA020101）

摘　　要：乳腺颗粒细胞瘤（GCTB）是Schwann细胞来源、发生于乳腺的罕见良性肿瘤，极少出现恶性倾向。GCTB无论是在临床表现上，还是在其影像学上都与乳腺癌极为相似。通常GCTB是良性、孤立的病变，但是包括恶性GCTB在内的非典型乳腺颗粒细胞瘤仍可以表现出多中心病灶，甚至与乳腺癌共存。目前组织病理学以及免疫组化是确诊乳腺颗粒细胞瘤的金标准。局部扩大切除术是目前主要的治疗方法。Granular cell tumor of the breast （GCTB） is a rare tumor which stems from Schwann cells. It is a largely benign tumor, but in the literature extremely infrequent cases can exhibit malignant characteristics. It tends to a particular problem as its characteristics are similar with breast carcinoma macroscopically, clinically, and radiologically. Typically, GCTB is benign and solitary lesion, yet including atypical GCTB and malignant GCTB, they can co-localize with breast malignancies multicentricity. The histopathological and immunohistochemical detection is the gold standard for diagnosis of GCTB up to now. And local expanded resection is the main treatment method at present.

关 键 词：乳腺肿瘤/诊断/治疗 颗粒细胞瘤/诊断/治疗 综述 

分 类 号：R737.9[医药卫生—肿瘤]