Oculyzer眼前节分析仪引导的准分子激光个性化手术治疗角膜斑翳的远期视觉质量评价  

Anterior chamber optical quality evaluation of oculyzer-guided, customized PTK for irregular astigmatism induced by corneal macula

作　　者：胡裕坤[1] 马怿民 高晓唯[1] 李文静[1] 郭云林[1] 董晶[1] 

机构地区：[1]解放军第474医院屈光手术中心,乌鲁木齐830013

出　　处：《中华眼视光学与视觉科学杂志》2016年第7期404-408,共5页Chinese Journal Of Optometry Ophthalmology And Visual Science

摘　　要：目的评价Oculyzer眼前节分析仪引导的准分子激光个体化切削手术治疗角膜斑翳的远期视觉质量。方法回顾性研究。选取2011年2月至2013年8月在解放军第474医院屈光手术中心治疗的6例（8眼）角膜斑翳患者，进行Oculyzer眼前节分析仪引导的个体化准分子激光手术，术后1个月、3个月、6个月、1年复查，分析术后散光、表面变异指数（ISV）、高度非对称性指数（IHA）、垂直非对称性指数（IVA）、高度轴偏心指数（IHD）及角膜总像差、低阶像差、总高阶像差、球差（C13）、水平彗差（C8）、垂直彗差（C9）、四叶草像差（C11），评价远期的视觉质量。治疗前后各数据比较采用配对样本t检验。结果术后6个月柱镜度为（0．16±0．19）D，与术前相比差异有统计学意义（t=3．801，P〈0．05）。术后1年，C13、C8、C9、C11与术前相比差异没有统计学意义，ISV、IHA、IVA、IHD及角膜总像差、总低阶像差、总高阶像差与术前相比差异均有统计学意义（t=-3．452、-4．907、-3．476、-4．353、-4．608、-4．548、-3．770．P〈0．05）。结论Oculyzer眼前节分析仪引导的个体化准分子激光手术治疗角膜斑翳远期视觉质量提高，安全有效。Objective To evaluate anterior chamber optical quality with oculyzer-guided, customized phototherapeutic keratectomy （PTK） for irregular astigmatism induced by corneal indentations. Methods This was a retrospective study. Six patients （8 eyes） with corneal indentations who were treated from February 2011 to August 2013 in the Department of Ophthalmology at the 474th Hospital of the Chinese People＇s Liberation Army were included in the study. All patients underwent oculyzer-guided, customized PTK and were followed up at 1 month, 3 months, 6 months and 1 year postoperatively. Postoperative astigmatism, index of surface variance （ISV）, index of height asymmetry （IHA）, index of vertical asymmetry （IVA）, index of height decentration （IHD）, corneal aberration, lower order aberrations, higher order aberrations, spherical aberrations （C13）, horizontal coma （C8）, vertical coma （C9）, and clover aberrations （Cll） were evaluated after the operation at 1 month, 3 months, 6 months, 1 year. A paired t-test was used for comparison of the data before and after treatment. Results After 6 months, the astigmatic refractive error was 0.16＋0.19 D, and the difference was significant compare with preoperation （t=3.801, P〈0.05）. There were no significant differences in the C13, C8, C9 or Cll. However, the differences in ISV, IHA, IVA, IHD, total aberrations, lower order aberrations, and higher order aberrations were statistically significant （t=-3.452, -4.907, -3.476, -4.353, -4.608, -4.548, -3.770, P〈0.05）. Conclusion Oculyzer-guided, customized PTK for irregular astigmatism induced by corneal indentation is safe and effective, visual quality improved.

关 键 词：角膜地形图 屈光性角膜切削术 角膜外科手术 激光 个性化手术 角膜斑翳 

分 类 号：R779.63[医药卫生—眼科]