神经内镜与神经导航辅助显微镜下经鼻蝶入路垂体腺瘤切除术的临床疗效对比分析  

Comparison of clinical efficacy between neuroendoscope- and neuronavigation-assisted microsurgeries for single-nostril transsphenoidal pituitary adenomas

作　　者：陈露露[1] 李健[1] 苏贺先[1] 

机构地区：[1]蚌埠医学院第一附属医院神经外科,233000

出　　处：《中国微侵袭神经外科杂志》2016年第7期307-309,共3页Chinese Journal of Minimally Invasive Neurosurgery

摘　　要：目的探讨神经内镜与神经导航辅助显微镜下经鼻蝶入路垂体腺瘤切除术的临床疗效及优缺点。方法将54例垂体腺瘤病人随机分两组,其中30例病人行神经内镜下单鼻孔蝶窦入路垂体腺瘤切除术(神经内镜组),24例病人行神经导航辅助显微镜下单鼻孔蝶窦入路垂体腺瘤切除术(导航显微镜组)。分析两组病人的术后并发症发生率、住院时间、手术时间和肿瘤全切率。结果神经内镜组与导航显微镜组在术后并发症发生率、肿瘤全切率方面差异无统计学意义(P>0.05)。导航显微镜组手术时间短于神经内镜组,而神经内镜组术后住院时间明显短于导航显微镜组(P<0.05)。结论神经内镜与神经导航辅助显微镜下经鼻蝶入路垂体腺瘤切除术的临床疗效相当,需结合病人情况实施治疗。Objective To explore the clinical efficacy, advantages and disadvantages of neuroendoscope- and neuronavigation-assisted microsurgeries for single-nostril transsphenoidal pituitary adenomas. Methods A total of 54 patients with pituitary adenomas was randomly divided into two groups, including 30 patients treated by neuroendoscopic endonasal transsphenoidal surgery（neuroendoscopy group） and 24 treated by neuronavigation-assisted endonasal transsphenoidal surgery（neuronavigation microsurgery group）. The rate of postoperative complication, the postoperative hospital stay, operation time and total resection rate of the two groups were analyzed. Results There were no significant differences in postoperative complication rate and tumor total resection rate between the two groups（P 〉 0.05）. The operation time was less in the neuronavigation microsurgery group than in the neuroendoscopy group, but the postoperative hospital stay of neuroendoscopy group was less than that of neuronavigation microsurgery group（ P 〈 0. 05）.Conclusions The clinical efficacy of neuroendoscope- and neuronavigation-assisted microsurgeries for single-nostril transsphenoidal pituitary adenomas are similar, and the treatment should be executed according to the condition of patients.

关 键 词：垂体肿瘤 神经内镜 显微镜 神经导航 入路 经鼻蝶 

分 类 号：R736.4[医药卫生—肿瘤] R651.1[医药卫生—临床医学]