韦氏智力量表各分项测验遗传度分析的双生子研究  

The Twin Study of the Heritability on the Component Table in the Wechsler Intelligence Scale

作　　者：覃青[1] 傅一笑[2] 蒙华庆[2] 向慧[1] 黄颖[1] 周于[1] 张茂兰[1] 蒋继泽[3] 

机构地区：[1]贵州省人民医院,贵州贵阳550002 [2]重庆医科大学附属第一医院 [3]贵阳市肺科医院

出　　处：《中国医学创新》2016年第23期6-9,共4页Medical Innovation of China

基　　金：国家自然科学基金(30470625)

摘　　要：目的：双生子法探索遗传对各分项智力的影响。方法：从重庆市主城区募集6~16岁的双生子，共募集122对双生子，采用中国修订版韦氏儿童智力量表评对双生子进行智力评定。并采取双生子颊黏膜标本以提取DNA进行卵型鉴定。评估双生子两个个体分值的相关系数并计算各智力指标的遗传度。结果：最终有卵型鉴定结果的共102对，其言语智商、操作智商、总智商遗传度分别为0.282、0.314、0.359，其中言语量表中的算术、词汇遗传度分别为0.360、0.266，操作量表中的木块图遗传度为0.296。结论：遗传因素对操作智商及总智商影响作用较大，言语智商受环境因素影响较大，遗传因素对各测验指标的影响作用按高低顺序排列分别为算术、木块图、词汇。Objective：Using twins methods to explore the influence of genetic factor on each item of intelligence. Method：There were 122 pairs of twins aged 6-16 years who lived the urban district of Chongqing city, the intelligence was assessed by using the Wechsler intelligence scale for children.And the twins buccal mucosa samples was took for DNA extraction of egg type identification.The correlation coefficient of the score was evaluated in the two individual of the twin,the heritability of intelligence indexes was calculate.Result：Eventually,102 pairs had egg type identification results.The total IQ of heritability were 0.359,verbal IQ were 0.282,performance IQ were 0.314.The arithmetic and vocabulary of the heritability were 0.360 and 0.266 in the verbal scale,the heritability of the block diagram were 0.296 in the performance scale.Conclusion：The more influence of genetic on PIQ and FIQ, the more influence of environment on the verbal IQ,the influence of genetic factors on the test index is arranged according to the order from high to low,there are respectively arithmetic, block diagram, and vocabulary.

关 键 词：双生子 中国修订版韦氏儿童智力量表 智力发育 遗传度 

分 类 号：R394[医药卫生—医学遗传学]