飞秒激光辅助的LASIK治疗高度近视术后高阶像差和角膜后表面高度的变化  

Changes of high order aberration and posterior corneal surface height after femtosecond laser assisted LASIK for high myopia

作　　者：朱冉[1] 程蕾[1] 龙克利[1] 顾明珠[1] 李全德[1] 

机构地区：[1]徐州市眼病防治研究所徐州市第一人民医院眼科,江苏省徐州市221002

出　　处：《眼科新进展》2016年第8期757-759,共3页Recent Advances in Ophthalmology

基　　金：2014年徐州市科技计划项目(编号:KC14SH070)~~

摘　　要：目的分析飞秒激光LASIK术后角膜后表面变化和角膜前表面高阶像差变化。方法选择我院于2014年2月至8月收治的52例(104眼)高度近视患者,随机分为对照组和观察组,各26例。两组患者均在本院行LASIK术,对照组接受传统术式,观察组给予飞秒激光辅助手术,比较两组患者术后高阶像差和角膜后表面高度变化。结果观察组术后1个月鼻上、颞下、鼻下和角膜顶点的角膜后表面高度与对照组比较,差异均有统计学意义(均为P<0.05)。观察组术后3个月四个象限内及角膜顶点的角膜后表面高度与对照组比较,差异均有统计学意义(均为P<0.05)。观察组和对照组术后1个月、3个月的四个象限内及角膜顶点的角膜后表面高度比较,差异均有统计学意义(均为P<0.05)。观察组术后6个月彗差、初级球差显著低于对照组,差异均有统计学意义(均为P<0.05);观察组总高阶像差均方根值与对照组比较,差异无统计学意义(P>0.05);观察组和对照组总高阶像差均方根值、彗差、初级球差较术前均显著升高,差异均有统计学意义(均为P<0.05)。结论飞秒激光辅助的LASIK术后角膜前表面高阶像差和角膜后表面高度变化相对较小,是一种理想的辅助LASIK技术。Objective To analyze the changes of high order aberration and posterior corneal surface height after femtosecond laser assisted LASIK for high myopia. Methods Fifty-tw o patients with high myopia were chosen in our hospital from February 2014 to August 2014 were chosen and randomly divided into control group,observation group,and 26 cases in each group.The patients of tw o groups in our hospital all received LASIK,the control group accepted conventional surgery,observation group was given femtosecond laser assisted surgery. The postoperative high-order aberration and posterior corneal surface height changes in tw o groups were compared. Results C ompared with control group,there were statistical differences in the posterior corneal surface height under the quarters of superior-nose,inferior-temporal,inferior-nose and corneal vertex at postoperative 1 month in the observation group（ all P 〈 0. 05）. At postoperative3 months,there were significant differences in the posterior corneal surface height in four quadrants and corneal vertex betw een the observation group and control group（ all P 〈 0. 05）. There were statistical differences in the posterior corneal surface height in four quadrants and corneal vertex of the observation group and control group betw een postoperative 1 month and 3 months（ all P 〈 0. 05）. At postoperative 6 months,the coma and primary spherical aberration in the observation group were significantly low er than those in the control group,the difference were statistically significant（ all P 〈 0. 05）. There was no statistical difference in root mean square of total high order aberration betw een tw o groups（ P 〉 0. 05）. The postoperative root mean square of total high order aberration,coma and primary spherical aberration of tw o groups were all higher than preoperation,the differences were statistically significant（ all P 〈 0. 05）. Conclusion C hanges of high order aberration and posterior corneal surface height after femtosecond laser assisted LASIK for high

关 键 词：LASIK 飞秒激光 PENTACAM 角膜后表面 

分 类 号：R778[医药卫生—眼科]