帕金森病患者睡眠障碍的临床特点研究  

The clinical characteristics of Parkinson's patients sleep disorders research

作　　者：辛华栋[1] 

机构地区：[1]邯郸市第一医院神经内科,河北邯郸056007

出　　处：《中西医结合心血管病电子杂志》2016年第15期10-12,共3页Cardiovascular Disease Electronic Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的分析帕金森病(Parkinson’s disease,PD)患者睡眠障碍的临床特征,评价PD患者睡眠质量及可能的影响因素。方法采用统一帕金森病评定量表(Unified Parkinson’s disease rating scale,UPDRS)、改良Hoehn-Yahr分期、帕金森病睡眠量表(Parkinson's disease sleep scale,PDSS)、汉密尔顿抑郁量表(Hamilton depression scale,HAMD)、爱泼沃斯思睡量表(Epworth sleeping scale,ESS)及简易智能精神状态检查量表(Minimum mental state examination,MMSE)对PD患者病情及睡眠情况进行评定,并与对照组进行分析比较。结果 PD组PDSS总评分为(81.37士19.11)分,显著低于对照组的(119.78士13.96)分,差异有统计学意义(P<0.05)。PD组ESS平均得分(7.08±3.98)分,显著高于对照组的(4.25±3.32)分,差异有统计学意义(P<0.05)。PD患者睡眠障碍与年龄、HAMD及MMSE评分结果呈等级正相关。结论 PD患者睡眠障碍的发生率高,以入睡困难和睡眠维持障碍最常见,并受年龄、抑郁、认知状态等因素影响,与H-Y分期无关,临床应重视睡眠障碍的治疗。Objective To analyse the Parkinson＇s disease,Parkinson＇s diseases,PD）and clinical features of patients with sleep disorders, evaluation of the influence factors of sleep quality and possible PD patients.Methods The Unified Parkinson＇s disease rating scale（Unified Parkinson ＇s diseases, rating scale and UPDRS）,modified Hoehn-Yahr stage,sleep scale for Parkinson＇s disease（Parkinson＇ s diseases, sleep scale, PDSS）,Hamilton depression rating scale（Hamilton ＇scale, HAMD）,Love splashing voss drowsiness scale（Epworth sleeping scale, ESS）and simple intelligence scale for mental state examination（Minimum getting state examination, MMSE） for PD patients and to assess sleep conditions, and compared with the control group were analyzed.Results Into PD group PDSS judgement（81.37 and 19.11）, significantly lower than in the control group（119.78 and 13.96）, the difference was statistically significant（P 0.05）. PD group average ESS score（7.08 ＋ 3.98）, significantly higher than that of control group（4.25-3.32）, the difference was statistically significant（P 0.05）.PD patients with sleep disorders and age, HAMD and MMSE score results were four grades.Conclusion The prevalence of sleep disorders is high in patients with PD, with difficulty falling asleep and maintaining sleep disorder, the most common and affected by the factors such as age, depression and cognitive state, has nothing to do with H- Y in installment,clinical should pay attention to the treatment of sleep disorders.

关 键 词：帕金森病 睡眠障碍 临床特点 

分 类 号：R741.05[医药卫生—神经病学与精神病学]