基于重大基本公共卫生项目的大肠肿瘤危险因素的病例对照研究  

A case-control study on risk factors of colorectal tumor based on major basic public health program

作　　者：彭艳英 陈伟 马翠 顾华玲 

机构地区：[1]上海市金山区朱泾社区卫生服务中心,上海201599

出　　处：《职业与健康》2016年第14期1960-1962,共3页Occupation and Health

摘　　要：目的探究大肠肿瘤发病相关危险因素,为大肠癌的针对性防治提供参考依据。方法采用以社区为基础的1∶1配对病例对照研究方法,选取2013年5月—2015年1月上海市金山区朱泾社区卫生服务中心的303例大肠肿瘤患者为病例组,根据年龄和性别配比选取相同数量的对照,采用上海市金山区统一的筛查表收集资料,通过统计分析进行危险因素判定。结果研究结果表明肠息肉史、一级亲属肠癌史、吸烟史可导致大肠肿瘤的发病增加（P〈0.05）。肠息肉史OR=13.57,95%CI：1.53~119.98;一级亲属肠癌史OR=1.23,95%CI：1.23~21.45;吸烟史OR=2.01,95%CI：1.18~3.42。结论大肠肿瘤的发生与肠息肉史、一级亲属肠癌史、吸烟史密切相关,对此应重点加强监督防控。[Objective]To investigate the risk factors of colorectal tumor and provide references for preventing these diseases.[Methods]1 ∶1 matched case-control study based on community was adopted. 303 patients with colorectal tumor in Zhujing Community Health Service Center in Jinshan District of Shanghai from May 2013 to January 2015 were enrolled in the case group,and 303 age and sex matched controls were collected. The uniform questionnaire of Jinshan District of Shanghai was used to collect the information,and the data were analyzed for identifying risk factors. [Results]History of intestinal polyps（OR=13.57,95%CI：1.53-119.98）,family history of first-degree relatives with colorectal cancer（OR=1.23,95%CI：1.23-21.45）and smoking history（OR=2.01,95%CI：1.18-3.42）were associated with colorectal tumor（P〈0.05）.[Conclusion]The occurrence of colorectal tumor is closely related to history of intestinal polyps,family history of first-degree relatives with colorectal cancer,and smoking history. The targeted supervision and control should be strengthened.

关 键 词：大肠肿瘤 危险因素 1∶1配比病例对照研究 

分 类 号：R735.3[医药卫生—肿瘤]