^18F-FDG PET-CT评价淋巴瘤骨髓浸润的临床价值  

The clinical utility of 18F-FDG PET-CT for detection of bone marrow infiltration in lymphoma

作　　者：吴媛[1] 刘小兰[1] 苏丽萍[1] 

机构地区：[1]山西医科大学附属肿瘤医院血液科,太原030013

出　　处：《国际肿瘤学杂志》2016年第8期634-637,共4页Journal of International Oncology

基　　金：山西省卫生厅科技攻关计划（2011044）

摘　　要：淋巴瘤骨髓浸润对疾病的诊断、分期、治疗方案选择及预后评估至关重要，常规部位的骨髓活检为主要检测手段，但假阴性率高。^18氟脱氧葡萄糖-正电子发射计算机断层显像（^18F-FDG PET-CT）将形态学与功能代谢整合在一起，具有高敏感性、高特异性及功能显像的优点，^18F-FDG PET-CT为淋巴瘤骨髓浸润的诊断、疾病分期及预后评估提供了新的途径。Bone marrow infiltration in lymphoma is crucial to the disease diagnosis, staging, treatment options and prognostic evaluation. Although bone marrow biopsy is the main detecting method, it has high false negative rate. At present, ^18F-fluorodeoxyglucose positron emission tomography-computed tomography （^18F-FDG PET-CT） technology which is integrating morphological characteristics with metabolic function provides a new way for the diagnosis, staging and prognostic evaluation of bone marrow infiltration in lymphoma due to its advantages of high sensitivity, high specificity and functional image.

关 键 词：淋巴瘤 骨髓 氟脱氧葡萄糖F18 正电子发射断层显像术 

分 类 号：R733.1[医药卫生—肿瘤] R730.44[医药卫生—临床医学]