CT引导下射频消融联合化疗治疗肺癌的疗效观察  

Observation of Efficacy of Radiofrequency Ablation Guided by CT Combined with Chemotherapy for Lung Cancer

作　　者：陈照亮[1] 刘红[1] 杨会利[1] 张娟[1] 高玉凯[1] 蒋雪超[1] 

机构地区：[1]山东省滨州市中心医院,251700

出　　处：《实用癌症杂志》2016年第8期1293-1295,共3页The Practical Journal of Cancer

摘　　要：目的分析CT引导下射频消融联合化疗治疗中晚期周围性非小细胞肺癌(NSCLC)的临床疗效。方法选取Ⅲ、Ⅳ期周围性NSCLC患者70例,随机分为观察组和对照组,各35例。对照组给予吉西他滨+顺铂(GP方案)进行化疗,观察组在对照组的基础上给予CT引导下射频消融进行治疗。比较两组患者的近期、远期疗效以及不良反应发生情况。结果观察组近期、远期疗效明显优于对照组(P<0.05);观察组行射频消融术后出现少量咯血4例(11.4%)、气胸3例(8.6%)、发热3例(8.6%),经对症支持治疗后均恢复,两组患者其他化疗不良反应比较差异无统计学意义(P>0.05)。结论 CT引导下射频消融联合化疗治疗中晚期周围性非小细胞肺癌临床疗效显著,不良反应少,值得临床推广应用。Objective To explore the clinical effect of radiofrequency ablation guided by CT combined with chemothera- py for later staged peripheral non-small cell lung cancer （ NSCLC ）. Methods 70 cases of staged III or IV periphera NSCLC were divided into 2 groups evenly. The control group were treated with GP, and the observation group were treated with radiofrequency ablation guide by ct combined with GP. The short-term and long-term efficacy and the complications of the 2 groups were com- pared. Results The short-term and long-term efficacy of the observation group were better than those of the control group. In the observation group, there had 4 cases of hemoptysis （ 11.4% ） ,3 cases of pneumothorax （ 8.6% ） ,3 cases of fever （ 8.6% ） , all of these cases recovered after proper treatment. There were no obvious difference between the 2 groups in other adverse reactions （P 〉 0.05）. Conclusion Radiofrequency ablation guide by ct combined with chemotherapy for later staged periphera NSCLC is ef- fective with less adverse reactions. It is worthy of clinical application.

关 键 词：CT 射频消融 化疗 非小细胞肺癌 

分 类 号：R734.2[医药卫生—肿瘤]