八珍汤在原发性肝癌介入治疗后的应用  

Clinical observation on Bazhen Decoction used for primary liver cancer patients after TACE treatment

作　　者：寇小妮[1] 郝明霞[1] 解新科[1] 畅辉[2] 

机构地区：[1]陕西中医药大学第一附属医院肝病科,陕西咸阳712000 [2]陕西中医药大学第一附属医院介入科,陕西咸阳712000

出　　处：《现代肿瘤医学》2016年第18期2920-2922,共3页Journal of Modern Oncology

摘　　要：目的:观察八珍汤对原发性肝癌介入治疗术后不良反应的干预及临床疗效。方法:收集陕西中医药大学第一附属医院肝病科2010年6月至2013年6月中晚期原发性肝癌患者共68例,随机分成治疗组34例和对照组34例,均行TACE治疗,1次/4周共2次,并行常规对症支持治疗,治疗组予加用八珍汤1包,2次/d,对照组不予中药治疗。两组疗程均为8周,治疗8周时随访一次。观察患者临床总证候、临床症状、生化指标、生活质量(KPS)变化、不良反应和1年、2年生存率。结果:八珍汤临床总证候治疗有效率优于对照组(P<0.05),对口干、腹胀、乏力和纳呆症状及生化指标的改善优于对照组(P<0.05),可明显提高患者生活质量(P<0.05),减轻介入治疗后不良反应,对照组2年生存率显著低于治疗组患者(P<0.05)。结论:应用八珍汤对原发性肝癌介入治疗术后不良反应疗效较好,可改善患者生化指标、缓解症状、延长生存时间,值得进一步研究其有效性。Objective： To observe the adverse reactions and clinical curative effect of Bazhen Decoction after interventional treatment for primary hepatocellular carcinoma. Methods： A total of 68 patients with primary liver cancer,randomly divided into treatment group（ 34 cases） and control group（ 34 cases）,were treated with conventional treatment and conventional support. Patients in the treatment group took 1 package of eight Jane soup,2 times / d,control group did not. Results： Bazhen Decoction group total effectiveness was better than that of control group（ P〈0. 05）,dry counterpart,abdominal distension,fatigue,slow stay symptoms and biochemical indicators were better than that of control group（ P〈0. 05）,obviously improve the patients quality of life（ P〈0. 05）,reduce adverse reaction after interventional therapy. In control group,2- year survival rate was significantly lower than the treatment group（ P〈0. 05）. Conclusion： Bazhen Decoction after interventional treatment for primary hepatocellular carcinoma,can improve patients＇ biochemical indicators,relieve symptoms,prolong the survival time,improve patient quality of life.

关 键 词：八珍汤 原发性肝癌 介入治疗 

分 类 号：R735.7[医药卫生—肿瘤]